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Catalog Number:
02370
CAS Number:
86060-86-8
Fmoc-L-alanine pentafluorophenyl ester
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-L-Ala-OPfp
Documents
$22.03 /1G
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Product Information

Fmoc-L-alanine pentafluorophenyl ester is a highly versatile compound widely utilized in peptide synthesis and drug development. This compound features a unique pentafluorophenyl group, which enhances its reactivity and stability, making it an excellent choice for researchers focused on the synthesis of complex peptides. Its Fmoc (fluorenylmethyloxycarbonyl) protecting group allows for selective deprotection under mild conditions, facilitating the efficient assembly of peptides in solid-phase synthesis.

Researchers in the fields of medicinal chemistry and biochemistry will find Fmoc-L-alanine pentafluorophenyl ester particularly beneficial for developing novel therapeutic agents and studying protein interactions. Its ability to improve the solubility and bioavailability of peptides makes it a valuable tool in pharmaceutical formulations. Additionally, the compound's unique properties can lead to enhanced yields and purity in peptide synthesis compared to traditional methods, making it a preferred choice for professionals aiming for high-quality results in their research and applications.

Synonyms
Fmoc-L-Ala-OPfp
CAS Number
86060-86-8
Purity
≥ 99% (HPLC)
Molecular Formula
C24H16F5NO4
Molecular Weight
477.4
MDL Number
MFCD00065612
Melting Point
170 - 185 ºC
Appearance
White powder
Optical Rotation
[a]D20 = - 20 ± 2º (C=1 in CHCl3)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Ala-OPfp
CAS Number
86060-86-8
Purity
≥ 99% (HPLC)
Molecular Formula
C24H16F5NO4
Molecular Weight
477.4
MDL Number
MFCD00065612
Melting Point
170 - 185 ºC
Appearance
White powder
Optical Rotation
[a]D20 = - 20 ± 2º (C=1 in CHCl3)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-alanine pentafluorophenyl ester is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex structures efficiently. Its stability and reactivity make it ideal for solid-phase peptide synthesis.
  • Drug Development: In pharmaceutical research, it is used to develop new drug candidates, particularly in the design of peptide-based therapeutics. The Fmoc protecting group facilitates selective reactions, enhancing the drug design process.
  • Bioconjugation: The compound is valuable in bioconjugation techniques, where it helps attach biomolecules to surfaces or other molecules. This application is crucial in developing targeted drug delivery systems.
  • Analytical Chemistry: It is employed in analytical methods to study protein interactions and modifications, providing insights into biological processes and disease mechanisms.
  • Material Science: The compound can be used in the development of functional materials, such as hydrogels, that have applications in tissue engineering and regenerative medicine.

Citations