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Catalog Number:
03226
CAS Number:
189337-28-8
Fmoc-O-tert-butyl-L-threoninol
Purity:
≥ 98.5% (HPLC)
Synonym(s):
Fmoc-L-Threoninol(tBu), Fmoc-L-Thr(tBu)-ol
Documents
$110.70 /1G
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Product Information

Fmoc-O-tert-butyl-L-threoninol is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This protected amino alcohol serves as a crucial building block in the development of peptide-based therapeutics, enabling researchers to create complex structures with enhanced stability and bioactivity. Its unique Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection, facilitating the efficient assembly of peptides while maintaining the integrity of sensitive functional groups.

In addition to its application in peptide synthesis, Fmoc-O-tert-butyl-L-threoninol is also valuable in the study of protein interactions and drug design. Its ability to mimic natural amino acids makes it an excellent candidate for the development of novel inhibitors and modulators in pharmaceutical research. Researchers appreciate its high purity and reliable performance, making it an essential tool in both academic and industrial laboratories focused on drug discovery and development.

Synonyms
Fmoc-L-Threoninol(tBu), Fmoc-L-Thr(tBu)-ol
CAS Number
189337-28-8
Purity
≥ 98.5% (HPLC)
Molecular Formula
C23H29NO4
Molecular Weight
383.5
MDL Number
MFCD00235950
PubChem ID
53434695
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 8 ± 1 º (C=2 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Threoninol(tBu), Fmoc-L-Thr(tBu)-ol
CAS Number
189337-28-8
Purity
≥ 98.5% (HPLC)
Molecular Formula
C23H29NO4
Molecular Weight
383.5
MDL Number
MFCD00235950
PubChem ID
53434695
Appearance
White to off-white powder
Optical Rotation
[a]D20 = 8 ± 1 º (C=2 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-O-tert-butyl-L-threoninol is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in solid-phase peptide synthesis, allowing for the selective modification of amino acids. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, it aids in the design of peptide-based drugs. The ability to easily remove the Fmoc group allows for the creation of active pharmaceutical ingredients with high purity.
  • Bioconjugation: This chemical is used in the conjugation of peptides to other biomolecules, enhancing the delivery and efficacy of therapeutics in targeted drug delivery systems.
  • Research in Protein Engineering: It plays a crucial role in modifying proteins for various applications, including enzyme engineering and the development of novel biomaterials.
  • Academic Research: Its versatility makes it a valuable tool in academic laboratories for studying protein interactions and functions, contributing to advancements in biochemistry and molecular biology.

Citations