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Catalog Number:
16534
CAS Number:
188348-00-7
Boc-D-cyclohexylglycinol
Synonym(s):
(R-2-(tert-Butoxycarbonylamino)-2-cyclohexylethanol
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Product Information

Boc-D-cyclohexylglycinol is a versatile compound widely utilized in the fields of medicinal chemistry and pharmaceutical research. This compound, also known as tert-butyl N-[(1R)-1-cyclohexyl-2-hydroxyethyl]carbamate, features a unique structure that enhances its potential as a building block in the synthesis of various bioactive molecules. Its distinctive cyclohexyl group contributes to its lipophilicity, making it an attractive candidate for drug development, particularly in the design of peptide mimetics and other therapeutic agents.

Researchers appreciate Boc-D-cyclohexylglycinol for its ability to facilitate the formation of stable peptide bonds, which is crucial in the synthesis of complex peptides. Its protective Boc (tert-butoxycarbonyl) group allows for selective deprotection, enabling chemists to manipulate the compound with precision during synthetic processes. This compound has shown promise in applications ranging from the development of enzyme inhibitors to the creation of novel drug candidates, making it a valuable addition to any laboratory focused on innovative therapeutic solutions.

Synonyms
(R-2-(tert-Butoxycarbonylamino)-2-cyclohexylethanol
CAS Number
188348-00-7
Molecular Formula
C13H25NO3
Molecular Weight
243.34
MDL Number
MFCD04112590
PubChem ID
22037861
Melting Point
83-87ºC
Conditions
Store at 0-8°C
General Information
Synonyms
(R-2-(tert-Butoxycarbonylamino)-2-cyclohexylethanol
CAS Number
188348-00-7
Molecular Formula
C13H25NO3
Molecular Weight
243.34
MDL Number
MFCD04112590
PubChem ID
22037861
Melting Point
83-87ºC
Conditions
Store at 0-8°C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Boc-D-cyclohexylglycinol is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, enhancing the efficiency of the process by preventing unwanted reactions during chemical modifications.
  • Drug Development: Its unique structure allows for the design of novel pharmaceuticals, particularly in the development of compounds targeting neurological disorders, where cyclohexyl groups can improve bioavailability.
  • Chiral Catalysis: Boc-D-cyclohexylglycinol is used as a chiral auxiliary in asymmetric synthesis, providing researchers with a reliable method to produce enantiomerically pure compounds, crucial in the pharmaceutical industry.
  • Bioconjugation: The compound is employed in bioconjugation techniques, facilitating the attachment of drugs to biomolecules, which can enhance therapeutic efficacy and specificity in targeted drug delivery systems.
  • Research in Organic Chemistry: It serves as a versatile building block in organic synthesis, allowing chemists to create complex molecules with specific functional groups, thereby advancing research in material science and medicinal chemistry.

Citations