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Catalog Number:
03198
CAS Number:
139551-83-0
Fmoc-L-leucinol
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-Leu-ol
Documents
$45.47 /1G
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Product Information

Fmoc-L-leucinol is a versatile building block widely utilized in peptide synthesis and medicinal chemistry. This compound, known for its high purity and stability, serves as a crucial intermediate in the preparation of Fmoc-protected amino acids, which are essential for the development of peptide-based therapeutics. Its unique structure allows for easy incorporation into various peptide sequences, making it an invaluable resource for researchers focusing on drug discovery and development.

In addition to its role in peptide synthesis, Fmoc-L-leucinol exhibits potential applications in the synthesis of complex natural products and in the development of novel materials. Its favorable solubility and compatibility with various coupling reagents enhance its utility in diverse chemical reactions. Researchers and industry professionals can leverage Fmoc-L-leucinol to streamline their synthesis processes, ultimately leading to more efficient and effective outcomes in their projects.

Synonyms
Fmoc-Leu-ol
CAS Number
139551-83-0
Purity
≥ 98% (HPLC)
Molecular Formula
C21H25NO3
Molecular Weight
339.4
MDL Number
MFCD00235932
PubChem ID
19978438
Melting Point
131-134 °C
Appearance
White powder
Optical Rotation
[a]D20 = -22 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-Leu-ol
CAS Number
139551-83-0
Purity
≥ 98% (HPLC)
Molecular Formula
C21H25NO3
Molecular Weight
339.4
MDL Number
MFCD00235932
PubChem ID
19978438
Melting Point
131-134 °C
Appearance
White powder
Optical Rotation
[a]D20 = -22 ± 2º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-L-leucinol is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in peptide synthesis, allowing for the selective modification of amino acids while preventing unwanted reactions. Its stability under various conditions makes it a preferred choice for chemists.
  • Drug Development: In pharmaceutical research, Fmoc-L-leucinol is instrumental in the design of peptide-based drugs, particularly those targeting specific receptors. Its ability to enhance bioactivity is crucial in developing effective therapeutics.
  • Bioconjugation: The compound is used in bioconjugation processes, linking biomolecules to create targeted drug delivery systems. This application is vital in improving the efficacy and reducing side effects of treatments.
  • Material Science: Fmoc-L-leucinol finds applications in creating functional materials, such as hydrogels, which are used in tissue engineering and regenerative medicine, offering innovative solutions for wound healing and drug release.
  • Research in Protein Engineering: It is also employed in protein engineering to modify proteins for better stability and functionality, which is essential in various biotechnological applications, including enzyme design and antibody production.

Citations