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Catalog Number:
03186
CAS Number:
153815-59-9
Fmoc-γ-tert-butyl ester-L-glutamol
Purity:
≥ 98% (HPLC)
Synonym(s):
Fmoc-L-Glutamol(OtBu)
Documents
$130.80 /1G
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Product Information

Fmoc-g-tert-butyl ester-L-glutamol is a versatile compound widely utilized in peptide synthesis and medicinal chemistry. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amino acids during the synthesis of peptides. Its tert-butyl ester functionality enhances solubility and stability, making it an ideal choice for researchers working in organic synthesis and drug development. The compound's unique structure allows for efficient coupling reactions, facilitating the formation of complex peptide sequences with high purity and yield.

In practical applications, Fmoc-g-tert-butyl ester-L-glutamol serves as a key intermediate in the synthesis of bioactive peptides, which are crucial in pharmaceutical research and development. Its ability to provide a stable and easily removable protecting group streamlines the synthesis process, reducing the time and effort required for peptide assembly. Researchers in the fields of biochemistry and pharmacology will find this compound particularly beneficial for developing novel therapeutic agents and studying protein interactions.

Synonyms
Fmoc-L-Glutamol(OtBu)
CAS Number
153815-59-9
Purity
≥ 98% (HPLC)
Molecular Formula
C24H29NO5
Molecular Weight
411.5
MDL Number
MFCD00671687
PubChem ID
74681852
Appearance
White powder
Optical Rotation
[a]D20 = -11 ± 2º (C=1 in EtOAc)
Conditions
Store at 0-8 °C
General Information
Synonyms
Fmoc-L-Glutamol(OtBu)
CAS Number
153815-59-9
Purity
≥ 98% (HPLC)
Molecular Formula
C24H29NO5
Molecular Weight
411.5
MDL Number
MFCD00671687
PubChem ID
74681852
Appearance
White powder
Optical Rotation
[a]D20 = -11 ± 2º (C=1 in EtOAc)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fmoc-g-tert-butyl ester-L-glutamol is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in the synthesis of peptides, allowing for selective reactions. Its stability under various conditions makes it a preferred choice for researchers in organic chemistry.
  • Drug Development: It plays a crucial role in the development of pharmaceutical compounds, particularly in creating prodrugs that enhance bioavailability and therapeutic efficacy.
  • Bioconjugation: The compound can be used in bioconjugation processes, facilitating the attachment of biomolecules to drugs or diagnostic agents, which is essential in targeted therapies.
  • Research in Neuroscience: Its derivatives are explored in studies related to neurotransmitter systems, contributing to the understanding of neurological disorders and potential treatments.
  • Material Science: The compound is also investigated for its properties in developing new materials, particularly in creating polymers with specific functionalities for biomedical applications.

Citations