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Catalog Number:
26927
CAS Number:
19172-47-5
Lawesson's reagent
Purity:
≥ 98% (Assay)
Synonym(s):
2,4-Bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-dithione, 2,4-Bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide
Hazmat
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Product Information

Lawesson's reagent is a versatile chemical compound widely recognized for its role as a powerful thioketone and a key reagent in organic synthesis. This compound is particularly valued in the synthesis of thioketones and thioesters, making it an essential tool for researchers and industry professionals engaged in the development of pharmaceuticals, agrochemicals, and specialty chemicals. Its unique ability to facilitate the conversion of carbonyl compounds into their corresponding thio derivatives enhances its utility in various synthetic pathways.

Additionally, Lawesson's reagent is known for its efficiency in promoting the formation of sulfur-containing heterocycles, which are crucial in the design of biologically active molecules. Its application extends to the synthesis of complex natural products and the modification of existing compounds to improve their efficacy and selectivity. With its favorable reactivity profile and ability to streamline synthetic processes, Lawesson's reagent stands out as a preferred choice for chemists seeking reliable and effective solutions in their research and development endeavors.

Synonyms
2,4-Bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-dithione, 2,4-Bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide
CAS Number
19172-47-5
Purity
≥ 98% (Assay)
Molecular Formula
C14H14O2P2S4
Molecular Weight
404.48
MDL Number
MFCD00005171
PubChem ID
87949
Melting Point
218 - 228 °C (Lit.)
Appearance
Slight yellow to yellow powder/crystals
Conditions
Store at RT
General Information
Synonyms
2,4-Bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane-2,4-dithione, 2,4-Bis(4-methoxyphenyl)-1,3,2,4-dithiadiphosphetane 2,4-disulfide
CAS Number
19172-47-5
Purity
≥ 98% (Assay)
Molecular Formula
C14H14O2P2S4
Molecular Weight
404.48
MDL Number
MFCD00005171
PubChem ID
87949
Melting Point
218 - 228 °C (Lit.)
Appearance
Slight yellow to yellow powder/crystals
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Lawesson's reagent is widely utilized in research focused on:

  • Synthesis of Thioesters: It effectively converts carboxylic acids into thioesters, which are valuable intermediates in organic synthesis, particularly in the pharmaceutical industry.
  • Preparation of Thiophene Derivatives: This reagent is crucial for synthesizing thiophene compounds, which are important in materials science and organic electronics.
  • Functionalization of Aromatic Compounds: It allows for the selective introduction of sulfur into aromatic systems, enhancing the properties of compounds used in agrochemicals and dyes.
  • Pharmaceutical Development: Lawesson's reagent is used in the synthesis of various bioactive compounds, aiding in the development of new drugs with improved efficacy.
  • Research in Organosulfur Chemistry: It serves as a key tool for researchers exploring the chemistry of sulfur-containing compounds, contributing to advancements in multiple chemical fields.

Citations