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Catalog Number:
26506
CAS Number:
24424-99-5
Di-tert-butyl dicarbonate, 2.0M solution in THF
Purity:
≥ 99% (GC)
Synonym(s):
Boc anhydride, 2.0M solution in THF, Di-tert-butyl pyrocarbonate, 2.0M solution in THF
Hazmat
Documents
$58.39 /100ML
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Product Information

Di-tert-butyl dicarbonate is a versatile reagent widely utilized in organic synthesis, particularly in the field of peptide and amino acid chemistry. This compound serves as a protecting group for amines, enabling chemists to selectively modify functional groups without interference. Its 2.0M solution in THF (tetrahydrofuran) offers excellent solubility and reactivity, making it an ideal choice for various laboratory applications. Researchers appreciate its stability and ease of use, which streamline complex synthetic pathways and enhance overall efficiency.

In addition to its role in peptide synthesis, di-tert-butyl dicarbonate is also employed in the preparation of various pharmaceuticals and agrochemicals. Its ability to protect amines during chemical transformations allows for greater precision in the synthesis of intricate molecular structures. The compound's favorable properties, such as its high purity and reliable performance, make it a preferred choice among professionals seeking to optimize their synthetic processes. With its broad applicability and significant advantages over similar protecting groups, di-tert-butyl dicarbonate stands out as an essential tool in modern organic chemistry.

Synonyms
Boc anhydride, 2.0M solution in THF, Di-tert-butyl pyrocarbonate, 2.0M solution in THF
CAS Number
24424-99-5
Purity
≥ 99% (GC)
Molecular Formula
C10H18O5
Molecular Weight
218.25
MDL Number
MFCD00008805
PubChem ID
90495
Density
0.934 g/mL at 25 ?C
Appearance
Colorless transparent liquid
Boiling Point
65-67 ?C
Refractive Index
n20/D 1.408
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc anhydride, 2.0M solution in THF, Di-tert-butyl pyrocarbonate, 2.0M solution in THF
CAS Number
24424-99-5
Purity
≥ 99% (GC)
Molecular Formula
C10H18O5
Molecular Weight
218.25
MDL Number
MFCD00008805
PubChem ID
90495
Density
0.934 g/mL at 25 ?C
Appearance
Colorless transparent liquid
Boiling Point
65-67 ?C
Refractive Index
n20/D 1.408
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Di-tert-butyl dicarbonate, 2.0M solution in THF is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a protecting group for amines and alcohols, allowing chemists to selectively modify other parts of a molecule without interfering with these functional groups.
  • Pharmaceutical Development: It is commonly used in the synthesis of pharmaceutical intermediates, aiding in the creation of complex drug molecules by facilitating specific reactions.
  • Polymer Chemistry: The compound is employed in the preparation of polycarbonate materials, which are known for their durability and transparency, making them ideal for various applications including eyewear and electronic components.
  • Analytical Chemistry: It aids in the derivatization of compounds for improved detection and quantification in chromatographic techniques, enhancing the accuracy of analytical results.
  • Biotechnology: In bioconjugation processes, it is used to modify biomolecules, improving their stability and functionality for applications in drug delivery and diagnostics.

Citations