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Catalog Number:
26505
CAS Number:
24424-99-5
Di-tert-butyl dicarbonate, 1.0 M solution in THF
Purity:
≥ 99% (GC)
Synonym(s):
Boc anhydride, 1.0M solution in THF, Di-tert-butyl dicarbonate, 1.0M solution in THF
Hazmat
Documents
$43.87 /100ML
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Product Information

Di-tert-butyl dicarbonate is a versatile reagent widely utilized in organic synthesis, particularly in the protection of amines and alcohols. This compound, available as a 1.0M solution in THF, offers a convenient and effective means to temporarily shield functional groups during multi-step reactions. Its ability to form stable carbamate derivatives makes it an essential tool for chemists aiming to enhance the selectivity and yield of their synthetic pathways.

Researchers and industry professionals appreciate Di-tert-butyl dicarbonate for its ease of use and compatibility with various reaction conditions. It is particularly valuable in peptide synthesis, where it aids in the protection of amino acids, allowing for more complex structures to be assembled with precision. Additionally, its high solubility in THF ensures that it can be easily integrated into various reaction mixtures, streamlining the synthesis process. With its unique properties and practical applications, Di-tert-butyl dicarbonate stands out as a reliable choice for those engaged in advanced chemical research and development.

Synonyms
Boc anhydride, 1.0M solution in THF, Di-tert-butyl dicarbonate, 1.0M solution in THF
CAS Number
24424-99-5
Purity
≥ 99% (GC)
Molecular Formula
C10H18O5
Molecular Weight
218.25
MDL Number
MFCD00008805
PubChem ID
90495
Density
0.913
Appearance
Colorless transparent liquid
Boiling Point
65-67 ?C
Conditions
Store at 0-8 °C
General Information
Synonyms
Boc anhydride, 1.0M solution in THF, Di-tert-butyl dicarbonate, 1.0M solution in THF
CAS Number
24424-99-5
Purity
≥ 99% (GC)
Molecular Formula
C10H18O5
Molecular Weight
218.25
MDL Number
MFCD00008805
PubChem ID
90495
Density
0.913
Appearance
Colorless transparent liquid
Boiling Point
65-67 ?C
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Di-tert-butyl dicarbonate is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a protecting group for amines, allowing chemists to selectively modify other functional groups without affecting the amine. This is particularly useful in multi-step synthesis processes.
  • Pharmaceutical Development: In drug formulation, it helps in the protection of amino acids during peptide synthesis, enhancing the efficiency of producing complex pharmaceutical compounds.
  • Polymer Chemistry: It is employed in the synthesis of polymers where controlled functionalization is required, enabling the development of advanced materials with tailored properties.
  • Analytical Chemistry: The compound is used in sample preparation techniques, improving the stability and detectability of analytes in various analytical methods, such as HPLC.
  • Biotechnology: In the production of bioconjugates, it aids in the selective modification of biomolecules, which is crucial for developing targeted drug delivery systems and diagnostics.

Citations