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Catalog Number:
24616
CAS Number:
207291-81-4, 703-95-7
5-Fluoroorotic acid hydrate
Purity:
≥ 98% (HPLC)
Synonym(s):
5-Fluorouracil-4-carboxylic acid hydrate, 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid hydrate
Documents
$29.34 /1G
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Product Information

5-Fluoroorotic acid hydrate is a valuable compound in the field of pharmaceutical research and biochemistry, known for its role as a potent inhibitor of orotate phosphoribosyltransferase, an enzyme involved in pyrimidine metabolism. This compound is particularly significant in the development of anticancer therapies, as it has shown promise in selectively targeting cancer cells by disrupting nucleotide synthesis. Researchers utilize 5-Fluoroorotic acid hydrate in various studies aimed at understanding its effects on cell proliferation and its potential as a chemotherapeutic agent.

In addition to its applications in cancer research, this compound serves as a useful tool in genetic studies, particularly in the selection of transformed cells in molecular biology. Its unique properties allow for the effective screening of genetically modified organisms, making it an essential reagent in genetic engineering and synthetic biology. With its dual role in both therapeutic development and genetic research, 5-Fluoroorotic acid hydrate stands out as a versatile compound that can significantly contribute to advancements in medical and biological sciences.

Synonyms
5-Fluorouracil-4-carboxylic acid hydrate, 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid hydrate
CAS Number
207291-81-4, 703-95-7
Purity
≥ 98% (HPLC)
Molecular Formula
C5H3FN2O4·H2O
Molecular Weight
192.1
MDL Number
MFCD00150658
PubChem ID
16212749
Melting Point
246-258 ºC
Appearance
Pale yellow crystalline powder
Conditions
Store at 0-8 °C
General Information
Synonyms
5-Fluorouracil-4-carboxylic acid hydrate, 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid hydrate
CAS Number
207291-81-4, 703-95-7
Purity
≥ 98% (HPLC)
Molecular Formula
C5H3FN2O4·H2O
Molecular Weight
192.1
MDL Number
MFCD00150658
PubChem ID
16212749
Melting Point
246-258 ºC
Appearance
Pale yellow crystalline powder
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Fluoroorotic acid hydrate is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various antiviral and anticancer agents, aiding researchers in developing targeted therapies.
  • Biochemical Research: It is used in studies related to nucleic acid metabolism, helping scientists understand the role of orotic acid in cellular processes and its potential implications in diseases.
  • Genetic Studies: The compound is valuable in genetic research, particularly in the study of mutations and their effects on cellular function, providing insights into genetic disorders.
  • Plant Biology: Researchers utilize it to investigate the effects of fluorinated compounds on plant growth and development, contributing to agricultural science and crop improvement.
  • Analytical Chemistry: It serves as a standard in various analytical methods, ensuring accurate measurements and quality control in laboratory settings.

Citations