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Catalog Number:
24151
CAS Number:
13009-99-9
Mafenide acetate
Grade:
Meets USP specification
Purity:
98 - 102% (Assay by anhydrous basis)
Synonym(s):
4-(Aminomethyl)benzenesulfonamide acetate, α-Amino-p-toluensulfonamide monoacetate
Documents
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Product Information

Mafenide acetate is a sulfonamide compound recognized for its potent antibacterial properties, primarily used in the treatment of burn wounds. This compound acts effectively against a broad spectrum of gram-positive and gram-negative bacteria, making it a valuable asset in clinical settings, particularly in burn units. Its unique ability to penetrate the skin and maintain a therapeutic concentration at the site of infection enhances its efficacy, providing a crucial advantage over other topical antibiotics. Mafenide acetate is also utilized in various formulations, including creams and gels, ensuring ease of application and patient compliance.

In addition to its primary use in wound care, Mafenide acetate has potential applications in research settings, particularly in studies focused on antibiotic resistance and the development of new antimicrobial agents. Its distinctive mechanism of action, which involves the inhibition of bacterial folic acid synthesis, positions it as a critical compound for further exploration in pharmaceutical development. Researchers and healthcare professionals can rely on Mafenide acetate not only for its immediate therapeutic benefits but also for its contributions to advancing medical science.

Synonyms
4-(Aminomethyl)benzenesulfonamide acetate, α-Amino-p-toluensulfonamide monoacetate
CAS Number
13009-99-9
Purity
98 - 102% (Assay by anhydrous basis)
Grade
Meets USP specification
Molecular Formula
C7H10N2O2S·C2H4O2
Molecular Weight
246.29
MDL Number
MFCD00072089
PubChem ID
25590
Melting Point
162 - 171 ?C
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
4-(Aminomethyl)benzenesulfonamide acetate, α-Amino-p-toluensulfonamide monoacetate
CAS Number
13009-99-9
Purity
98 - 102% (Assay by anhydrous basis)
Grade
Meets USP specification
Molecular Formula
C7H10N2O2S·C2H4O2
Molecular Weight
246.29
MDL Number
MFCD00072089
PubChem ID
25590
Melting Point
162 - 171 ?C
Appearance
White to off-white crystalline powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mafenide acetate is widely utilized in research focused on:

  • Topical Antimicrobial Treatment: Commonly used in burn care, it helps prevent infections in severe burns, promoting faster healing and reducing complications.
  • Pharmaceutical Formulations: Serves as an active ingredient in creams and ointments, providing effective antimicrobial properties for various skin conditions.
  • Research in Dermatology: Used in studies to evaluate skin responses and treatment efficacy, aiding in the development of new dermatological therapies.
  • Veterinary Medicine: Applied in treating skin infections in animals, showcasing its versatility beyond human medicine.
  • Combination Therapies: Often used alongside other medications to enhance therapeutic outcomes, particularly in complex wound care scenarios.

Citations