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Catalog Number:
00522
CAS Number:
593-84-0
Guanidine thiocyanate
Grade:
Biotech Grade
Purity:
≥ 99% (Assay)
Synonym(s):
Guanidine isothiocyanate, Guanidinium thiocyanate
Hazmat
Documents
$20.20 /100G
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Product Information

Guanidine thiocyanate is a versatile chemical compound widely utilized in molecular biology and biochemistry, particularly for its role in nucleic acid extraction and purification. This compound acts as a chaotropic agent, effectively disrupting hydrogen bonds and facilitating the denaturation of proteins and nucleic acids. Its unique properties make it an essential reagent in the isolation of RNA and DNA from biological samples, ensuring high yields and purity. Researchers appreciate its efficiency in lysing cells and inactivating RNases, which is crucial for maintaining the integrity of nucleic acids during extraction processes.

In addition to its applications in nucleic acid research, guanidine thiocyanate is also employed in various industrial processes, including the synthesis of pharmaceuticals and agrochemicals. Its ability to solubilize proteins and enhance reaction rates makes it a valuable component in formulations requiring protein stabilization. With its broad range of applications and effectiveness in molecular biology, guanidine thiocyanate stands out as a reliable choice for researchers and industry professionals seeking high-quality results in their work.

Synonyms
Guanidine isothiocyanate, Guanidinium thiocyanate
CAS Number
593-84-0
Purity
≥ 99% (Assay)
Grade
Biotech Grade
Molecular Formula
CH5N3·HSCN
Molecular Weight
118.16
MDL Number
MFCD00013027
PubChem ID
65046
Melting Point
116 - 121 ?C
Appearance
White to slightly off-white crystalline powder
Conditions
Store at RT
General Information
Synonyms
Guanidine isothiocyanate, Guanidinium thiocyanate
CAS Number
593-84-0
Purity
≥ 99% (Assay)
Grade
Biotech Grade
Molecular Formula
CH5N3·HSCN
Molecular Weight
118.16
MDL Number
MFCD00013027
PubChem ID
65046
Melting Point
116 - 121 ?C
Appearance
White to slightly off-white crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Guanidine thiocyanate is widely utilized in research focused on:

  • Nucleic Acid Extraction: This compound is a key reagent in isolating RNA and DNA from biological samples, making it essential for molecular biology studies.
  • Protein Denaturation: It effectively denatures proteins, which is crucial for studying protein structure and function, particularly in proteomics.
  • Cell Lysis: Used in cell lysis buffers, it helps break down cell membranes, facilitating the extraction of cellular components for analysis.
  • Diagnostic Applications: In clinical laboratories, it aids in the preparation of samples for various diagnostic tests, improving accuracy and reliability.
  • Research on Disease Mechanisms: Its role in studying cellular processes makes it valuable in research related to diseases, including cancer and viral infections.

Citations