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Catalog Number:
48037
CAS Number:
5580-20-1
2'-Deoxy-4-thiouridine
Purity:
≥ 95% (HPLC)
Synonym(s):
4-Thio-2'-dU, 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
Documents
$211.20 /100MG
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Product Information

2'-Deoxy-4-thiouridine is a modified nucleoside that plays a crucial role in molecular biology and biochemistry. This compound is recognized for its unique sulfur substitution at the 4-position of the uridine base, which enhances its stability and reactivity compared to standard nucleosides. Researchers utilize 2'-Deoxy-4-thiouridine in various applications, including the synthesis of nucleic acid analogs and as a tool in antiviral research. Its ability to incorporate into RNA and DNA makes it a valuable asset in studying genetic processes and developing therapeutic agents.

In addition to its applications in research, 2'-Deoxy-4-thiouridine has shown potential in drug development, particularly in the design of antiviral and anticancer therapies. Its unique properties allow for the exploration of novel mechanisms of action, making it a promising candidate for further investigation in pharmaceutical applications. The compound's versatility and effectiveness in enhancing nucleic acid stability make it an essential tool for scientists and researchers in the field.

Synonyms
4-Thio-2'-dU, 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
CAS Number
5580-20-1
Purity
≥ 95% (HPLC)
Molecular Formula
C9H12N2O4S
Molecular Weight
244.27
MDL Number
MFCD00058457
Melting Point
167 - 171 °C
Appearance
White to light yellow powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
4-Thio-2'-dU, 1-(2-Deoxy-b-D-erythro-pentofuranosyl)-4-thioxo-3,4-dihydro-2(1H)-pyrimidinone
CAS Number
5580-20-1
Purity
≥ 95% (HPLC)
Molecular Formula
C9H12N2O4S
Molecular Weight
244.27
MDL Number
MFCD00058457
Melting Point
167 - 171 °C
Appearance
White to light yellow powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2'-Deoxy-4-thiouridine is widely utilized in research focused on:

  • Nucleic Acid Research: This compound serves as a building block in the synthesis of modified nucleotides, aiding in the study of RNA and DNA structures and functions.
  • Antiviral Drug Development: Its unique thiol group enhances antiviral activity, making it a candidate for developing treatments against various viral infections.
  • Biochemical Assays: Used in assays to study enzyme interactions and nucleic acid binding, providing insights into cellular processes and potential therapeutic targets.
  • Gene Therapy: This compound can be incorporated into therapeutic oligonucleotides, improving stability and efficacy in gene therapy applications.
  • Pharmaceutical Formulations: Its properties allow for the creation of innovative drug formulations that can enhance bioavailability and therapeutic effects compared to traditional compounds.

Citations