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Catalog Number:
47385
CAS Number:
2044711-52-4
(R)-Fmoc-2-amino-4,4,4-trifluoro-butyric acid
Purity:
≥ 99.5% (Chirla HPLC)
Synonym(s):
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4,4,4-trifluorobutanoicacid
Documents
$110.00 /25MG
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Product Information

(R)-Fmoc-2-amino-4,4,4-trifluoro-butyric acid is a valuable compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorinated side chain, enhancing its stability and reactivity, making it an ideal choice for researchers focused on creating novel peptides with improved pharmacological properties. The Fmoc (9-fluorenylmethoxycarbonyl) protecting group allows for selective deprotection, facilitating the synthesis of complex peptides while minimizing side reactions.

In the pharmaceutical industry, (R)-Fmoc-2-amino-4,4,4-trifluoro-butyric acid is particularly beneficial for developing peptide-based therapeutics, including those targeting specific diseases or conditions. Its unique trifluoromethyl group contributes to increased lipophilicity, which can enhance the bioavailability of the resulting peptides. Researchers can leverage this compound to explore innovative drug formulations and optimize therapeutic efficacy, making it a crucial tool in modern medicinal chemistry.

Synonyms
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4,4,4-trifluorobutanoicacid
CAS Number
2044711-52-4
Purity
≥ 99.5% (Chirla HPLC)
Molecular Formula
C19H16F3NO4
Molecular Weight
379.33
MDL Number
MFCD30543425
PubChem ID
46737291
Appearance
White to off-white powder
Optical Rotation
[α]D20 = 24 ± 1 ° (C=1 in CH3CN)
Conditions
Store at RT
General Information
Synonyms
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4,4,4-trifluorobutanoicacid
CAS Number
2044711-52-4
Purity
≥ 99.5% (Chirla HPLC)
Molecular Formula
C19H16F3NO4
Molecular Weight
379.33
MDL Number
MFCD30543425
PubChem ID
46737291
Appearance
White to off-white powder
Optical Rotation
[α]D20 = 24 ± 1 ° (C=1 in CH3CN)
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-Fmoc-2-amino-4,4,4-trifluoro-butyric acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protective group in the synthesis of peptides, allowing chemists to selectively modify amino acids without affecting the rest of the molecule.
  • Pharmaceutical Development: It plays a crucial role in the design of new drugs, particularly in the development of peptide-based therapeutics, enhancing the stability and bioavailability of active compounds.
  • Bioconjugation: The trifluorobutyric acid moiety can be used in bioconjugation processes, facilitating the attachment of biomolecules to surfaces or other compounds, which is essential in drug delivery systems.
  • Research in Fluorinated Compounds: Its unique trifluoromethyl group offers insights into the behavior of fluorinated compounds, making it valuable for studies in medicinal chemistry and material science.
  • Analytical Chemistry: This compound can be utilized in analytical methods to improve the detection and quantification of various substances, aiding researchers in quality control and product development.

Citations