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Catalog Number:
46046
CAS Number:
455-18-5
4-(Trifluoromethyl)benzonitrile
Purity:
≥ 98% (GC)
Synonym(s):
4-Cyanobenzotrifluoride, α,α,α-Trifluoro-p-tolunitrile
Hazmat
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Product Information

4-(Trifluoromethyl)benzonitrile is a versatile compound known for its unique trifluoromethyl group, which enhances its reactivity and solubility in various organic solvents. This compound is widely utilized in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals, making it an essential building block in the chemical industry. Its ability to act as a potent electrophile allows for the development of complex molecular architectures, facilitating research in medicinal chemistry and material science.

Researchers and industry professionals appreciate 4-(Trifluoromethyl)benzonitrile for its role in the creation of fluorinated compounds, which often exhibit improved biological activity and stability. Its applications extend to the production of advanced materials and fine chemicals, where its trifluoromethyl group imparts desirable properties such as increased lipophilicity and enhanced metabolic stability. This compound stands out in the market due to its effectiveness in various synthetic pathways, making it a valuable asset for those looking to innovate in their respective fields.

Synonyms
4-Cyanobenzotrifluoride, α,α,α-Trifluoro-p-tolunitrile
CAS Number
455-18-5
Purity
≥ 98% (GC)
Molecular Formula
C8H4F3N
Molecular Weight
171.12
MDL Number
MFCD00001826
PubChem ID
67995
Melting Point
37 °C
Density
1.27
Appearance
White or colorless to light yellow powder to lump to clear liquid
Boiling Point
81 °C/20 mmHg
Conditions
Store at 2 - 8 °C
General Information
Synonyms
4-Cyanobenzotrifluoride, α,α,α-Trifluoro-p-tolunitrile
CAS Number
455-18-5
Purity
≥ 98% (GC)
Molecular Formula
C8H4F3N
Molecular Weight
171.12
MDL Number
MFCD00001826
PubChem ID
67995
Melting Point
37 °C
Density
1.27
Appearance
White or colorless to light yellow powder to lump to clear liquid
Boiling Point
81 °C/20 mmHg
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-(Trifluoromethyl)benzonitrile is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting neurological disorders.
  • Agricultural Chemicals: It is used in the formulation of agrochemicals, enhancing the efficacy of pesticides and herbicides, which helps in improving crop yields.
  • Material Science: The compound is incorporated into polymers and materials to impart desirable properties such as increased thermal stability and chemical resistance.
  • Fluorinated Compounds Research: It plays a significant role in the study of fluorinated compounds, which are known for their unique properties, making it valuable in various chemical research applications.
  • Analytical Chemistry: 4-(Trifluoromethyl)benzonitrile is utilized as a standard in analytical methods, aiding in the detection and quantification of other chemical substances in complex mixtures.

Citations