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Catalog Number:
40476
CAS Number:
86521-05-3
2-[(Trimethylsilyl)ethynyl]pyridine
Purity:
≥ 98% (GC)
Synonym(s):
(2-Pyridylethynyl)trimethylsilane
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Product Information

2-[(Trimethylsilyl)ethynyl]pyridine is a versatile compound widely utilized in organic synthesis and materials science. This compound, characterized by its unique trimethylsilyl group, enhances the reactivity of the ethynyl moiety, making it an excellent building block for the synthesis of various functionalized organic molecules. Its ability to participate in cross-coupling reactions and other transformations makes it invaluable in the development of pharmaceuticals, agrochemicals, and advanced materials. Researchers appreciate its stability and ease of handling, which facilitate its incorporation into complex synthetic pathways.

In addition to its synthetic applications, 2-[(Trimethylsilyl)ethynyl]pyridine serves as a key intermediate in the preparation of novel ligands and catalysts, contributing to advancements in catalysis and materials development. Its unique properties allow for the fine-tuning of electronic and steric characteristics in target molecules, making it a preferred choice for chemists aiming to optimize reaction conditions. With its broad applicability and significant advantages over similar compounds, this chemical is essential for professionals seeking innovative solutions in their research and development efforts.

Synonyms
(2-Pyridylethynyl)trimethylsilane
CAS Number
86521-05-3
Purity
≥ 98% (GC)
Molecular Formula
C10H13NSi
Molecular Weight
175.31
MDL Number
MFCD00066349
PubChem ID
522859
Melting Point
40 - 43 °C
Density
0.94 g/mL
Appearance
Colorless to light yellow liquid
Boiling Point
90 °C / 18 mmHg (Lit.)
Refractive Index
n20D 1.53
Conditions
Store at ≤ -4 °C
General Information
Synonyms
(2-Pyridylethynyl)trimethylsilane
CAS Number
86521-05-3
Purity
≥ 98% (GC)
Molecular Formula
C10H13NSi
Molecular Weight
175.31
MDL Number
MFCD00066349
PubChem ID
522859
Melting Point
40 - 43 °C
Density
0.94 g/mL
Appearance
Colorless to light yellow liquid
Boiling Point
90 °C / 18 mmHg (Lit.)
Refractive Index
n20D 1.53
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-[(Trimethylsilyl)ethynyl]pyridine is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a versatile building block in organic synthesis, allowing chemists to create complex molecules efficiently.
  • Pharmaceutical Development: It is used in the development of new pharmaceuticals, particularly in the synthesis of compounds with potential therapeutic effects, enhancing drug discovery processes.
  • Material Science: The compound plays a role in the development of advanced materials, including polymers and nanomaterials, which can lead to innovative applications in electronics and coatings.
  • Analytical Chemistry: It is employed as a reagent in analytical chemistry for the detection and quantification of various substances, improving the accuracy of analytical methods.
  • Research in Catalysis: This chemical is significant in catalytic processes, facilitating reactions that are essential in both academic and industrial research, leading to more sustainable practices.

Citations