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Catalog Number:
40198
CAS Number:
112204-57-6
5-Bromo-2-fluorophenylboronic acid
Purity:
97 - 105% (Assay by titration)
Synonym(s):
5-Bromo-2-fluorobenzeneboronic acid
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$112.57 /5G
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Product Information

5-Bromo-2-fluorophenylboronic acid is a versatile boronic acid derivative that plays a crucial role in organic synthesis and medicinal chemistry. This compound is recognized for its ability to participate in Suzuki-Miyaura cross-coupling reactions, making it invaluable for the formation of carbon-carbon bonds. Its unique structure, featuring both bromine and fluorine substituents, enhances its reactivity and selectivity in various chemical transformations. Researchers and industry professionals utilize this compound in the development of pharmaceuticals, agrochemicals, and advanced materials, where precision and efficiency are paramount.

In addition to its applications in synthetic chemistry, 5-Bromo-2-fluorophenylboronic acid serves as a key intermediate in the synthesis of biologically active compounds. Its compatibility with a range of functional groups allows for the creation of complex molecular architectures, facilitating the discovery of new therapeutic agents. The compound's stability and ease of handling further contribute to its appeal in laboratory settings, making it an essential tool for chemists aiming to innovate in drug development and material science.

Synonyms
5-Bromo-2-fluorobenzeneboronic acid
CAS Number
112204-57-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BBrFO2
Molecular Weight
218.82
MDL Number
MFCD05664307
PubChem ID
10856974
Melting Point
174 °C (Lit.)
Appearance
White to light yellow crystalline powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
5-Bromo-2-fluorobenzeneboronic acid
CAS Number
112204-57-6
Purity
97 - 105% (Assay by titration)
Molecular Formula
C6H5BBrFO2
Molecular Weight
218.82
MDL Number
MFCD05664307
PubChem ID
10856974
Melting Point
174 °C (Lit.)
Appearance
White to light yellow crystalline powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5-Bromo-2-fluorophenylboronic acid is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly in the development of drugs targeting cancer and other diseases. Its unique structure allows for the modification of drug properties to enhance efficacy.
  • Organic Synthesis: It is commonly used in cross-coupling reactions, such as Suzuki-Miyaura coupling, to form carbon-carbon bonds. This application is crucial in creating complex organic molecules found in agrochemicals and fine chemicals.
  • Material Science: The compound is employed in the development of advanced materials, including polymers and nanomaterials, which can be used in electronics and coatings. Its boronic acid functionality allows for the formation of stable complexes with various substrates.
  • Bioconjugation: In biochemistry, it is utilized for labeling biomolecules, enabling researchers to track and study proteins and nucleic acids. This application is essential in drug delivery systems and diagnostic tools.
  • Fluorescent Probes: The compound can be modified to create fluorescent probes for imaging applications in biological research. These probes help visualize cellular processes, providing insights into disease mechanisms and treatment responses.

Citations