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Catalog Number:
37891
CAS Number:
75607-67-9
2-Fluoroadenine 9-β-D-arabinofuranoside 5'-monophosphate
Purity:
≥ 98% (Assay by titration , HPLC)
Synonym(s):
2-F-ara-AMP, Fludarabine monophosphate
Documents
$40.96 /25MG
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Product Information

2-Fluoroadenine 9-b-D-arabinofuranoside 5'-monophosphate is a specialized nucleotide analog that plays a significant role in biochemical research and pharmaceutical development. This compound is recognized for its potential applications in the study of nucleic acid metabolism and the development of antiviral and anticancer therapies. Its unique structure, featuring a fluorine atom, enhances its stability and bioactivity, making it a valuable tool for researchers investigating cellular processes and drug mechanisms.

In practical applications, 2-Fluoroadenine 9-b-D-arabinofuranoside 5'-monophosphate has been utilized in the synthesis of modified nucleotides, which can be employed in the design of novel therapeutics targeting specific pathways in cancer cells or viral infections. Its ability to mimic natural nucleotides allows for the exploration of new treatment strategies, providing researchers with a powerful means to investigate and manipulate biological systems. This compound stands out for its potential to improve the efficacy of existing treatments while minimizing side effects, making it an essential addition to any research laboratory focused on molecular biology and pharmacology.

Synonyms
2-F-ara-AMP, Fludarabine monophosphate
CAS Number
75607-67-9
Purity
≥ 98% (Assay by titration , HPLC)
Molecular Formula
C10H13FN5O7P
Molecular Weight
365.21
MDL Number
MFCD00866418
PubChem ID
3368
Melting Point
203 ?C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = 11 - 13 ° (C=0.5 in H2O)
Conditions
Store at -10 °C
General Information
Synonyms
2-F-ara-AMP, Fludarabine monophosphate
CAS Number
75607-67-9
Purity
≥ 98% (Assay by titration , HPLC)
Molecular Formula
C10H13FN5O7P
Molecular Weight
365.21
MDL Number
MFCD00866418
PubChem ID
3368
Melting Point
203 ?C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = 11 - 13 ° (C=0.5 in H2O)
Conditions
Store at -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Fluoroadenine 9-b-D-arabinofuranoside 5'-monophosphate is widely utilized in research focused on:

  • Antiviral Research: This compound is being explored for its potential in developing antiviral therapies, particularly against viral infections like HIV and hepatitis. Its structural similarities to nucleotides allow it to interfere with viral replication.
  • Biochemical Studies: It serves as a valuable tool in studying enzyme kinetics and metabolic pathways, helping researchers understand the role of nucleotides in cellular processes.
  • Drug Development: The compound is being investigated as a lead candidate for new drug formulations, particularly in oncology, due to its ability to inhibit certain cancer cell lines.
  • Genetic Research: It is utilized in the synthesis of modified RNA molecules, aiding in the development of gene therapies and RNA-based treatments.
  • Pharmaceutical Formulations: The compound is being integrated into various pharmaceutical products for enhanced efficacy and targeted delivery in therapeutic applications.

Citations