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Catalog Number:
37511
CAS Number:
42340-98-7
(R)-(-)-1-(1-Naphthyl)ethyl isocyanate
Purity:
≥ 90% (GC)
Synonym(s):
(R)-NEI, Isocyanic acid (R)-(-)-1-(1-Naphthyl)ethyl ester
Hazmat
Documents
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Product Information

(R)-(-)-1-(1-Naphthyl)ethyl isocyanate is a versatile compound widely utilized in organic synthesis and pharmaceutical development. This chiral isocyanate is recognized for its ability to participate in various chemical reactions, particularly in the formation of urethanes and carbamates, making it a valuable intermediate in the synthesis of biologically active molecules. Its unique naphthyl group enhances its reactivity and selectivity, allowing researchers to create complex structures with precision.

In the pharmaceutical industry, (R)-(-)-1-(1-Naphthyl)ethyl isocyanate has been employed in the development of novel drugs, particularly in the synthesis of chiral compounds that exhibit specific biological activities. Its application extends to materials science, where it serves as a building block for advanced polymers and coatings. The compound's ability to form stable linkages and its compatibility with various functional groups make it an essential tool for chemists seeking to innovate in drug design and material formulation.

Synonyms
(R)-NEI, Isocyanic acid (R)-(-)-1-(1-Naphthyl)ethyl ester
CAS Number
42340-98-7
Purity
≥ 90% (GC)
Molecular Formula
C13H11NO
Molecular Weight
197.24
MDL Number
MFCD00004015
PubChem ID
602753
Density
1.13 (Lit.)
Appearance
Clear colorless to light yellow to light orange liquid
Refractive Index
n20/D 1.61 (Lit.)
Optical Rotation
[a]20D = -40 to -50 ° (C=5 in Toluene)
Conditions
Store at 0 - 10 °C
General Information
Synonyms
(R)-NEI, Isocyanic acid (R)-(-)-1-(1-Naphthyl)ethyl ester
CAS Number
42340-98-7
Purity
≥ 90% (GC)
Molecular Formula
C13H11NO
Molecular Weight
197.24
MDL Number
MFCD00004015
PubChem ID
602753
Density
1.13 (Lit.)
Appearance
Clear colorless to light yellow to light orange liquid
Refractive Index
n20/D 1.61 (Lit.)
Optical Rotation
[a]20D = -40 to -50 ° (C=5 in Toluene)
Conditions
Store at 0 - 10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-(-)-1-(1-Naphthyl)ethyl isocyanate is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, particularly in creating compounds with specific biological activities.
  • Polymer Chemistry: It is used in the production of isocyanate-based polymers, which are essential in the manufacture of flexible foams, coatings, and adhesives, providing durability and resistance to wear.
  • Material Science: The compound contributes to the development of advanced materials, including those with unique thermal and mechanical properties, making it valuable in industries such as automotive and aerospace.
  • Agricultural Chemicals: It plays a role in the synthesis of agrochemicals, enhancing crop protection products that are more effective and environmentally friendly.
  • Research Applications: In academic and industrial laboratories, it is used as a reagent for studying reaction mechanisms and developing new synthetic methodologies, aiding in the advancement of chemical knowledge.

Citations