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Catalog Number:
30780
CAS Number:
716-61-0
1R,2R-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol
Purity:
≥ 99% (Assay)
Synonym(s):
D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol, Chloramphenicol base
Hazmat
Documents
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Product Information

(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is a versatile compound widely utilized in pharmaceutical research and development. This chiral amino alcohol features a nitrophenyl group, making it a valuable intermediate in the synthesis of various bioactive molecules. Its unique structure allows for applications in the development of pharmaceuticals, particularly in the creation of antihypertensive agents and other therapeutic compounds. Researchers appreciate its ability to facilitate the design of selective inhibitors and modulators, enhancing the efficacy of drug formulations.

Additionally, this compound's stability and reactivity make it suitable for use in organic synthesis, where it can serve as a building block for more complex molecules. Its potential in medicinal chemistry is underscored by its role in the synthesis of compounds with significant biological activity. With its favorable properties, (1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol stands out as a key ingredient for researchers aiming to innovate in drug discovery and development.

Synonyms
D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol, Chloramphenicol base
CAS Number
716-61-0
Purity
≥ 99% (Assay)
Molecular Formula
C9H12N2O4
Molecular Weight
212.2
MDL Number
MFCD00078126
PubChem ID
92743
Melting Point
159.5-166 ?C
Appearance
White or almost white crystalline powder
Optical Rotation
[a]20D = -28 to -30.5º (C=2.4 in 1N HCl)
Conditions
Store at 0-8 °C
General Information
Synonyms
D-(-)-threo-2-Amino-1-(p-nitrophenyl)-1,3-propanediol, Chloramphenicol base
CAS Number
716-61-0
Purity
≥ 99% (Assay)
Molecular Formula
C9H12N2O4
Molecular Weight
212.2
MDL Number
MFCD00078126
PubChem ID
92743
Melting Point
159.5-166 ?C
Appearance
White or almost white crystalline powder
Optical Rotation
[a]20D = -28 to -30.5º (C=2.4 in 1N HCl)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(1R,2R)-(-)-2-Amino-1-(4-nitrophenyl)-1,3-propanediol is widely utilized in research focused on:

  • Pharmaceutical Development: This compound serves as a key intermediate in the synthesis of various pharmaceuticals, particularly those targeting neurological disorders, due to its ability to cross the blood-brain barrier.
  • Biochemical Research: It is used in the study of enzyme interactions and protein binding, helping researchers understand biological processes and develop new therapeutic strategies.
  • Analytical Chemistry: The compound acts as a standard in chromatographic techniques, aiding in the accurate quantification of similar compounds in complex mixtures.
  • Material Science: Its properties make it suitable for developing novel materials, such as drug delivery systems, which can enhance the efficacy of treatments by targeting specific tissues.
  • Environmental Monitoring: This chemical is employed in the detection and analysis of pollutants, contributing to environmental protection efforts by identifying harmful substances in water and soil.

Citations