Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
29648
CAS Number:
914399-96-5
(R)-Fmoc-2-amino-3-tert-butoxy-2-methyl-propionic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
Fmoc-α-Me-D-Ser(tBu)-OH
Documents
$170.00 /25MG
Pack Size Availability Price
Request Bulk Quote
Product Information

(R)-Fmoc-2-amino-3-tert-butoxy-2-methyl-propionic acid is a versatile compound widely utilized in peptide synthesis and drug development. This amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is essential for the selective protection of amines during solid-phase peptide synthesis. Its unique tert-butoxy group enhances solubility and stability, making it an ideal choice for researchers looking to optimize their synthetic pathways.

In the pharmaceutical industry, (R)-Fmoc-2-amino-3-tert-butoxy-2-methyl-propionic acid is particularly valuable in the development of bioactive peptides and therapeutic agents. Its ability to facilitate the formation of complex peptide structures allows for the exploration of new drug candidates with improved efficacy and specificity. Researchers appreciate its compatibility with various coupling reagents and its role in enhancing the yield of desired products. This compound stands out for its efficiency in streamlining peptide synthesis, making it a preferred choice for both academic and industrial applications.

Synonyms
Fmoc-α-Me-D-Ser(tBu)-OH
CAS Number
914399-96-5
Purity
≥ 99% (HPLC)
Molecular Formula
C23H27NO5
Molecular Weight
397.47
MDL Number
MFCD26793608
PubChem ID
146025879
Appearance
White solid or powder
Optical Rotation
[a]D20 = -14 ± 2 ° (C=1 in Diethyl ether) [a]D20 = -9 ± 1 ° (C=1 in AcOET)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Fmoc-α-Me-D-Ser(tBu)-OH
CAS Number
914399-96-5
Purity
≥ 99% (HPLC)
Molecular Formula
C23H27NO5
Molecular Weight
397.47
MDL Number
MFCD26793608
PubChem ID
146025879
Appearance
White solid or powder
Optical Rotation
[a]D20 = -14 ± 2 ° (C=1 in Diethyl ether) [a]D20 = -9 ± 1 ° (C=1 in AcOET)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(R)-Fmoc-2-amino-3-tert-butoxy-2-methyl-propionic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a key building block in the synthesis of peptides, allowing researchers to create complex molecules for drug development and biochemical studies.
  • Drug Discovery: Its unique structure enhances the stability and bioavailability of peptide-based drugs, making it valuable in the pharmaceutical industry for developing new therapeutic agents.
  • Bioconjugation: The Fmoc protecting group facilitates selective reactions, enabling the attachment of biomolecules to surfaces or other compounds, which is crucial in creating targeted drug delivery systems.
  • Research in Neuroscience: This chemical is used in the synthesis of neuropeptides, which are important for studying neurological functions and developing treatments for neurodegenerative diseases.
  • Custom Synthesis Services: Many contract research organizations utilize this compound to provide tailored synthesis solutions for clients in academia and industry, addressing specific research needs efficiently.

Citations