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Catalog Number:
14491
CAS Number:
467438-40-0
2S,4S-Fmoc-4-cyclohexylpyrrolidine-2-carboxylic acid
Purity:
≥ 99% (HPLC)
Synonym(s):
(2S,4S-Fmoc-4-cyclohexyl-Pro-OH
Documents
$72.31 /25MG
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Product Information

(2S,4S)-Fmoc-4-cyclohexyl-pyrrolidine-2-carboxylic acid is a versatile compound widely utilized in the field of peptide synthesis and drug development. This protected amino acid derivative is particularly valued for its ability to enhance the stability and solubility of peptides during synthesis, making it an essential building block for researchers in medicinal chemistry. Its unique cyclohexyl side chain contributes to the compound's hydrophobic properties, which can improve the overall pharmacokinetic profile of the resulting peptides.

In addition to its applications in peptide synthesis, (2S,4S)-Fmoc-4-cyclohexyl-pyrrolidine-2-carboxylic acid is also employed in the development of novel therapeutic agents, particularly in the design of inhibitors and modulators for various biological targets. Researchers appreciate its ease of use and compatibility with standard coupling reagents, which streamlines the synthesis process. This compound stands out for its ability to facilitate the creation of complex peptide structures, thus holding significant potential for advancing drug discovery and development.

Synonyms
(2S,4S-Fmoc-4-cyclohexyl-Pro-OH
CAS Number
467438-40-0
Purity
≥ 99% (HPLC)
Molecular Formula
C26H29NO4
Molecular Weight
419.52
MDL Number
MFCD06656481
PubChem ID
4712595
Appearance
White powder
Optical Rotation
[a]D20 = -6.9 ± 1º (C=1 in DMF)
Conditions
Store at 0-8 °C
General Information
Synonyms
(2S,4S-Fmoc-4-cyclohexyl-Pro-OH
CAS Number
467438-40-0
Purity
≥ 99% (HPLC)
Molecular Formula
C26H29NO4
Molecular Weight
419.52
MDL Number
MFCD06656481
PubChem ID
4712595
Appearance
White powder
Optical Rotation
[a]D20 = -6.9 ± 1º (C=1 in DMF)
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(2S,4S)-Fmoc-4-cyclohexyl-pyrrolidine-2-carboxylic acid is widely utilized in research focused on

  • Peptide Synthesis: This compound is frequently used as a protecting group in solid-phase peptide synthesis, enhancing the efficiency and yield of peptide chains.
  • Drug Development: Its unique structure allows for the design of novel drug candidates, particularly in the development of peptide-based therapeutics.
  • Bioconjugation: The chemical serves as a versatile linker in bioconjugation processes, facilitating the attachment of biomolecules to various surfaces or carriers.
  • Research in Neuroscience: It is employed in the synthesis of compounds that target specific receptors in the brain, aiding in the study of neurological disorders.
  • Material Science: The compound can be utilized in creating advanced materials with specific properties, such as improved mechanical strength or thermal stability.

Citations