Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
12973
CAS Number:
219312-90-0
4-Fmoc-piperazine-2-carboxylic acid
Purity:
≥ 95% (HPLC)
Synonym(s):
4-Fmoc-Piz-2-carboxylic acid
Documents
$113.87 /250MG
Pack Size Availability Price
Request Bulk Quote
Product Information

4-Fmoc-piperazine-2-carboxylic acid is a versatile compound widely utilized in the field of peptide synthesis and drug development. This protected amino acid derivative features a fluorenylmethoxycarbonyl (Fmoc) group, which serves as a temporary protecting group for the amine functionality during the synthesis of peptides. Its unique structure allows for selective deprotection, facilitating the incorporation of piperazine into complex peptide sequences. Researchers and industry professionals appreciate its stability and compatibility with various coupling reagents, making it an ideal choice for solid-phase peptide synthesis.

In addition to its role in peptide synthesis, 4-Fmoc-piperazine-2-carboxylic acid is also valuable in medicinal chemistry for the development of piperazine-containing pharmaceuticals. Its ability to enhance solubility and bioavailability makes it a preferred choice in the formulation of drug candidates. The compound's application extends to the creation of novel therapeutic agents, particularly in the fields of neuropharmacology and anti-cancer research, where piperazine derivatives have shown promising activity. With its robust profile and practical applications, 4-Fmoc-piperazine-2-carboxylic acid stands out as a key reagent for advancing research and development in various chemical and pharmaceutical sectors.

Synonyms
4-Fmoc-Piz-2-carboxylic acid
CAS Number
219312-90-0
Purity
≥ 95% (HPLC)
Molecular Formula
C20H22N2O4
Molecular Weight
352.39
MDL Number
MFCD01076312
PubChem ID
4180461
Appearance
White solid
Conditions
Store at 0-8 °C
General Information
Synonyms
4-Fmoc-Piz-2-carboxylic acid
CAS Number
219312-90-0
Purity
≥ 95% (HPLC)
Molecular Formula
C20H22N2O4
Molecular Weight
352.39
MDL Number
MFCD01076312
PubChem ID
4180461
Appearance
White solid
Conditions
Store at 0-8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Fmoc-piperazine-2-carboxylic acid is widely utilized in research focused on:

  • Peptide Synthesis: This compound serves as a protecting group in peptide synthesis, allowing for the selective modification of amino acids without interfering with other functional groups. This is crucial for creating complex peptides in pharmaceutical research.
  • Drug Development: Its role in drug formulation is significant, particularly in the development of piperazine-based pharmaceuticals, which are known for their efficacy in treating various conditions, including anxiety and depression.
  • Bioconjugation: The compound is used in bioconjugation processes, where it helps attach biomolecules to surfaces or other molecules, enhancing the effectiveness of drug delivery systems.
  • Research in Neuroscience: Due to its structural similarity to neurotransmitters, it is employed in studies related to brain chemistry, aiding in the understanding of neurological disorders and potential treatments.
  • Material Science: It is also applied in the development of novel materials, particularly in creating polymers that require specific functional groups for enhanced properties, such as increased solubility or reactivity.

Citations