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Catalog Number:
06809
CAS Number:
81246-82-4
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-adenosine
Purity:
≥ 98% (HPLC)
Synonym(s):
5'-O-DMT-NBz-A
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Product Information

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-adenosine is a specialized nucleoside derivative that plays a pivotal role in biochemical research and pharmaceutical applications. This compound is particularly valuable in the synthesis of oligonucleotides, where its protective groups enhance the stability and efficiency of the synthesis process. Researchers appreciate its ability to facilitate the incorporation of modified nucleotides, which can lead to the development of novel therapeutics and diagnostic tools.

The unique structure of 5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-adenosine allows for selective reactions, making it an ideal candidate for applications in molecular biology, particularly in the design of antisense oligonucleotides and RNA interference studies. Its robust protective groups ensure that the nucleoside remains intact during the synthesis process, thereby improving yield and purity. This compound stands out for its versatility and effectiveness in enhancing the performance of nucleic acid-based technologies, making it a preferred choice for researchers aiming to push the boundaries of genetic research and therapeutic development.

Synonyms
5'-O-DMT-NBz-A
CAS Number
81246-82-4
Purity
≥ 98% (HPLC)
Molecular Formula
C38H35N5O7
Molecular Weight
673.72
MDL Number
MFCD00797466
PubChem ID
2829733
Appearance
White, off-white to yellow powder
Conditions
Store at ≤ -4 °C
General Information
Synonyms
5'-O-DMT-NBz-A
CAS Number
81246-82-4
Purity
≥ 98% (HPLC)
Molecular Formula
C38H35N5O7
Molecular Weight
673.72
MDL Number
MFCD00797466
PubChem ID
2829733
Appearance
White, off-white to yellow powder
Conditions
Store at ≤ -4 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-adenosine is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of oligonucleotides, which are essential for genetic research, diagnostics, and therapeutic applications.
  • Drug Development: It plays a significant role in the development of nucleoside-based drugs, particularly in antiviral and anticancer therapies, enhancing the efficacy of treatments.
  • Biotechnology: The compound is used in various biotechnological applications, including the design of RNA interference (RNAi) molecules that can silence specific genes, offering potential for gene therapy.
  • Research in Molecular Biology: It is utilized in studies involving DNA and RNA interactions, helping researchers understand fundamental biological processes and mechanisms.
  • Diagnostic Tools: This chemical is incorporated into diagnostic assays, improving the sensitivity and specificity of tests for various diseases, including infectious diseases and genetic disorders.

Citations