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Catalog Number:
04092
CAS Number:
103616-89-3
2-Chloro-L-phenylalanine
Purity:
≥ 99% (Chiral HPLC, HPLC)
Synonym(s):
L-Phe(2-Cl)-OH, o-Chloro-L-phenylalanine, H-Phe(2-Cl)-OH
Documents
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Product Information

2-Chloro-L-phenylalanine is a versatile amino acid derivative that plays a significant role in biochemical research and pharmaceutical applications. This compound is recognized for its ability to act as a selective inhibitor of certain enzymes, making it invaluable in studies related to protein synthesis and metabolic pathways. Its unique chlorinated structure enhances its reactivity and specificity, allowing researchers to explore its potential in drug development and therapeutic interventions.

In the field of neuroscience, 2-Chloro-L-phenylalanine has been utilized to investigate neurotransmitter systems, particularly in the context of studying the effects of amino acid transporters. Additionally, its application in the synthesis of peptide-based drugs highlights its importance in medicinal chemistry. Researchers and industry professionals can leverage this compound for innovative solutions in drug formulation and biochemical assays, making it a critical tool in advancing scientific knowledge and therapeutic strategies.

Synonyms
L-Phe(2-Cl)-OH, o-Chloro-L-phenylalanine, H-Phe(2-Cl)-OH
CAS Number
103616-89-3
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C9H10ClNO2
Molecular Weight
199.6
MDL Number
MFCD00077921
PubChem ID
85679
Melting Point
227 - 235 ?C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]20D = -9.0 to -10.5 º (C=1 in H2O)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
L-Phe(2-Cl)-OH, o-Chloro-L-phenylalanine, H-Phe(2-Cl)-OH
CAS Number
103616-89-3
Purity
≥ 99% (Chiral HPLC, HPLC)
Molecular Formula
C9H10ClNO2
Molecular Weight
199.6
MDL Number
MFCD00077921
PubChem ID
85679
Melting Point
227 - 235 ?C
Appearance
White to off-white crystalline powder
Optical Rotation
[a]20D = -9.0 to -10.5 º (C=1 in H2O)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

2-Chloro-L-phenylalanine is widely utilized in research focused on:

  • Neuroscience Research: This compound serves as a tool for studying neurotransmitter systems, particularly in understanding the role of phenylalanine in brain function and disorders.
  • Pharmaceutical Development: It is used in the synthesis of novel drugs, especially those targeting amino acid metabolism, providing a pathway for developing therapeutic agents for metabolic disorders.
  • Biochemical Studies: Researchers apply it in enzyme inhibition studies, helping to elucidate mechanisms of action for various enzymes, which is crucial for drug design.
  • Protein Engineering: This chemical is employed in the design of modified proteins, allowing scientists to explore the effects of chlorine substitution on protein structure and function.
  • Anticancer Research: It has potential applications in cancer treatment studies, where its analogs may inhibit tumor growth by interfering with amino acid transport mechanisms.

Citations