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Catalog Number:
01947
CAS Number:
100898-63-3
5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine
Purity:
≥ 99% (HPLC)
Synonym(s):
5'-O-DMT-NAc-2'-dC
Documents
$22.03 /1G
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Product Information

5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine is a versatile nucleoside derivative that plays a crucial role in the synthesis of oligonucleotides and nucleic acid research. This compound is particularly valued for its protective groups, which enhance stability during chemical reactions, making it an essential building block in the development of DNA and RNA sequences. Its unique structure allows for efficient incorporation into various nucleic acid constructs, facilitating advancements in gene therapy, molecular diagnostics, and synthetic biology. Researchers appreciate its ability to improve yields and purity in oligonucleotide synthesis, thus streamlining workflows in laboratories.

Additionally, this compound's favorable solubility and compatibility with standard reagents make it an ideal choice for both academic and industrial applications. Its use in the synthesis of modified nucleotides opens up possibilities for creating novel therapeutics and diagnostic tools, positioning it as a valuable asset in the rapidly evolving field of molecular biology. With its proven track record in enhancing nucleic acid synthesis, 5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine continues to support innovative research and development initiatives.

Synonyms
5'-O-DMT-NAc-2'-dC
CAS Number
100898-63-3
Purity
≥ 99% (HPLC)
Molecular Formula
C32H33N3O7
Molecular Weight
571.7
MDL Number
MFCD05663669
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
General Information
Synonyms
5'-O-DMT-NAc-2'-dC
CAS Number
100898-63-3
Purity
≥ 99% (HPLC)
Molecular Formula
C32H33N3O7
Molecular Weight
571.7
MDL Number
MFCD05663669
Appearance
White to off-white powder
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

5'-O-(4,4'-Dimethoxytrityl)-N4-acetyl-2'-deoxycytidine is widely utilized in research focused on:

  • Nucleic Acid Synthesis: This compound serves as a key building block in the synthesis of oligonucleotides, which are essential for various genetic research applications, including gene editing and RNA interference.
  • Pharmaceutical Development: It plays a significant role in the development of antiviral and anticancer drugs by facilitating the design of nucleoside analogs that can inhibit viral replication or cancer cell growth.
  • Diagnostic Tools: The compound is used in the formulation of probes for molecular diagnostics, allowing for the detection of specific nucleic acid sequences in clinical samples, which is crucial for early disease diagnosis.
  • Biotechnology Research: Researchers utilize it in the study of cellular processes and gene expression, helping to unravel complex biological mechanisms and develop new biotechnological applications.
  • Gene Therapy: Its application in gene therapy is notable, as it can be incorporated into vectors that deliver therapeutic genes to target cells, providing potential treatments for genetic disorders.

Citations