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Catalog Number:
38438
CAS Number:
82419-36-1
Ofloxacin
Purity:
≥ 98% (HPLC)
Synonym(s):
9-Fluoro-3,7-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
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Product Information

Ofloxacin is a broad-spectrum fluoroquinolone antibiotic renowned for its effectiveness against a variety of bacterial infections. This compound is particularly valuable in treating respiratory tract infections, urinary tract infections, and skin infections, making it a vital tool in both clinical and pharmaceutical settings. Its unique mechanism of action involves inhibiting bacterial DNA gyrase and topoisomerase IV, which are essential for bacterial replication and survival. This specificity allows for targeted treatment, minimizing the impact on beneficial flora.

In addition to its therapeutic applications, Ofloxacin is also utilized in research settings, particularly in studies focused on antibiotic resistance and the development of new antimicrobial agents. Its favorable pharmacokinetic properties, including good oral bioavailability and tissue penetration, enhance its utility in various formulations, including tablets and injectable solutions. With its proven efficacy and versatility, Ofloxacin remains a critical component in the arsenal against bacterial infections, offering both healthcare professionals and researchers a reliable option for effective treatment.

Synonyms
9-Fluoro-3,7-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
CAS Number
82419-36-1
Purity
≥ 98% (HPLC)
Molecular Formula
C18H20FN3O4
Molecular Weight
361.37
MDL Number
MFCD00226105
PubChem ID
4583
Melting Point
262 - 264 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
9-Fluoro-3,7-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid
CAS Number
82419-36-1
Purity
≥ 98% (HPLC)
Molecular Formula
C18H20FN3O4
Molecular Weight
361.37
MDL Number
MFCD00226105
PubChem ID
4583
Melting Point
262 - 264 °C
Appearance
White to light yellow powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ofloxacin is widely utilized in research focused on:

  • Antibiotic Therapy: It is primarily used to treat bacterial infections, particularly those caused by gram-negative bacteria. This makes it invaluable in clinical settings for treating conditions like urinary tract infections and respiratory infections.
  • Veterinary Medicine: Ofloxacin is also applied in veterinary practices to treat infections in animals, ensuring the health and well-being of pets and livestock.
  • Pharmaceutical Research: Researchers often study ofloxacin to develop new formulations or improve existing ones, exploring its efficacy and safety profiles in various populations.
  • In Vitro Studies: It is used in laboratory settings to investigate bacterial resistance mechanisms, helping scientists understand how bacteria adapt to antibiotics.
  • Public Health Initiatives: Ofloxacin plays a role in addressing public health challenges, particularly in managing outbreaks of infectious diseases, making it a critical tool for healthcare professionals.

Citations