Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
37452
CAS Number:
3483-12-3, 27565-41-9
1,4-Dithio-DL-threitol
Grade:
Molecular Biology Grade
Purity:
≥ 99% (Assay by titration, Iodometry)
Synonym(s):
DTT, Cleland's reagent, threo-1,4-Dimercapto-2,3-butanediol
Documents
$36.65 /1G
Pack Size Availability Price
Request Bulk Quote
Product Information

1,4-Dithio-DL-threitol is a versatile compound known for its unique properties as a reducing agent and antioxidant. This dithiol compound features two thiol groups, making it particularly effective in various biochemical applications, including protein stabilization and enzyme activity modulation. Researchers often utilize 1,4-Dithio-DL-threitol in the preparation of samples for biochemical assays, where its ability to maintain reduced states is crucial for accurate results. Its application extends to the pharmaceutical industry, where it plays a role in drug formulation and development, particularly in stabilizing sensitive compounds that may be prone to oxidation.

Additionally, 1,4-Dithio-DL-threitol is recognized for its potential in the field of materials science, particularly in the synthesis of novel polymers and nanomaterials. Its unique structure allows for the formation of cross-linked networks, enhancing the mechanical properties of materials. This compound is also valuable in the study of redox biology, providing insights into cellular processes and the role of thiols in biological systems. With its multifaceted applications, 1,4-Dithio-DL-threitol stands out as a crucial reagent for researchers and industry professionals alike.

Synonyms
DTT, Cleland's reagent, threo-1,4-Dimercapto-2,3-butanediol
CAS Number
3483-12-3, 27565-41-9
Purity
≥ 99% (Assay by titration, Iodometry)
Grade
Molecular Biology Grade
Molecular Formula
C4H10O2S2
Molecular Weight
154.24
MDL Number
MFCD00004877
PubChem ID
19001
Melting Point
40 - 44 °C
Appearance
White crystals or free flowing powder
Boiling Point
125-130 °C/12 mm
Conditions
Store at 0 - 8 °C
General Information
Synonyms
DTT, Cleland's reagent, threo-1,4-Dimercapto-2,3-butanediol
CAS Number
3483-12-3, 27565-41-9
Purity
≥ 99% (Assay by titration, Iodometry)
Grade
Molecular Biology Grade
Molecular Formula
C4H10O2S2
Molecular Weight
154.24
MDL Number
MFCD00004877
PubChem ID
19001
Melting Point
40 - 44 °C
Appearance
White crystals or free flowing powder
Boiling Point
125-130 °C/12 mm
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

1,4-Dithio-DL-threitol is widely utilized in research focused on:

  • Antioxidant Applications: This compound acts as a potent antioxidant, helping to protect cells from oxidative stress. It is particularly valuable in biomedical research for developing therapies against diseases linked to oxidative damage.
  • Pharmaceutical Development: Its unique chemical structure allows it to be used in the synthesis of various pharmaceutical agents, enhancing drug efficacy and stability in formulations.
  • Biochemical Assays: Researchers employ it in biochemical assays to study redox reactions and enzyme activities, providing insights into metabolic pathways and disease mechanisms.
  • Cosmetic Formulations: The compound is incorporated into cosmetic products for its skin-protective properties, helping to improve skin health and appearance by combating free radicals.
  • Food Preservation: It is also explored as a natural preservative in the food industry, where it helps extend shelf life by preventing oxidative spoilage, making it a safer alternative to synthetic preservatives.

Citations