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Catalog Number:
01511
CAS Number:
1405-20-5
Polymyxin B sulfate salt
Grade:
USP
Antibiotic
Documents
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Product Information

Polymyxin B sulfate salt is a potent antibiotic compound widely recognized for its effectiveness against Gram-negative bacterial infections. This polypeptide antibiotic is particularly valuable in clinical settings, where it is utilized to treat serious infections caused by multidrug-resistant bacteria. Its unique mechanism of action disrupts the bacterial cell membrane, leading to cell death, making it an essential tool in the fight against infections that are resistant to conventional antibiotics.

In addition to its therapeutic applications, Polymyxin B sulfate salt is also employed in laboratory research, particularly in microbiology and biochemistry, where it serves as a selective agent for isolating and studying specific bacterial strains. Its ability to inhibit bacterial growth makes it a critical component in various experimental protocols. Researchers appreciate its stability and effectiveness, which contribute to reliable results in both clinical and research environments. With its broad spectrum of applications and proven efficacy, Polymyxin B sulfate salt remains a vital resource for healthcare professionals and researchers alike.

CAS Number
1405-20-5
Grade
USP
Molecular Formula
C55H96N16O13·2H2SO4
Molecular Weight
1385.0
MDL Number
MFCD00131991
PubChem ID
3083708
Appearance
White to almost white powder
Optical Rotation
[a]D20 = -90 to -78 ° (Lit.)
Conditions
Store at 0 - 8 °C
Potency
≥ 6000 IU/MG (dried basis)
General Information
CAS Number
1405-20-5
Grade
USP
Molecular Formula
C55H96N16O13·2H2SO4
Molecular Weight
1385.0
MDL Number
MFCD00131991
PubChem ID
3083708
Appearance
White to almost white powder
Optical Rotation
[a]D20 = -90 to -78 ° (Lit.)
Conditions
Store at 0 - 8 °C
Potency
≥ 6000 IU/MG (dried basis)
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
Yes
DEA-regulated
No
Warnings
-
Applications

Polymyxin B sulfate salt is widely utilized in research focused on:

  • Antibiotic Applications: It is primarily used as a topical antibiotic for treating infections caused by Gram-negative bacteria, making it essential in clinical settings for wound care and infection control.
  • Pharmaceutical Formulations: This compound is incorporated into various pharmaceutical products, particularly in formulations aimed at combating resistant bacterial strains, providing a critical tool for healthcare professionals.
  • Microbiological Research: Researchers use polymyxin B sulfate salt to study bacterial resistance mechanisms, helping to develop new strategies for antibiotic therapy and enhancing our understanding of microbial behavior.
  • Cell Culture Applications: It is often employed in cell culture to prevent bacterial contamination, ensuring the integrity and reliability of experimental results in biological research.
  • Veterinary Medicine: The compound is also used in veterinary applications to treat infections in animals, demonstrating its versatility and importance in both human and animal health.

Citations