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Catalog Number:
41924
CAS Number:
23491-45-4
Bisbenzimide H 33258
Purity:
≥ 98% (HPLC)
Synonym(s):
2'-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi(1H-benzimidazole)trihydrochloride, 2-[2-(4-Hydroxyphenyl)-6-benzimidazoyl]-6-(1-methyl-4-piperazyl)benzimidazoletrihydrochloride, BBIH, BXI-72
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$55.48 /25MG
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Product Information

Bisbenzimide H 33258 is a potent fluorescent dye widely utilized in molecular biology and biochemistry for its exceptional ability to bind to DNA. This compound is particularly valuable in fluorescence microscopy and flow cytometry, where it serves as a vital tool for visualizing cellular structures and assessing cell viability. Its high specificity for double-stranded DNA allows researchers to accurately quantify DNA content in various samples, making it indispensable in applications such as cell cycle analysis and apoptosis studies.

Moreover, Bisbenzimide H 33258's unique properties enable it to be employed in various assays, including those for detecting DNA damage and monitoring gene expression. Its compatibility with multiple imaging systems enhances its versatility, allowing for seamless integration into existing laboratory workflows. With its robust performance and reliability, this compound stands out as a preferred choice for researchers seeking precise and reproducible results in their studies.

Synonyms
2'-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi(1H-benzimidazole)trihydrochloride, 2-[2-(4-Hydroxyphenyl)-6-benzimidazoyl]-6-(1-methyl-4-piperazyl)benzimidazoletrihydrochloride, BBIH, BXI-72
CAS Number
23491-45-4
Purity
≥ 98% (HPLC)
Molecular Formula
C25H24N6O·3HCl
Molecular Weight
533.88
MDL Number
MFCD00012679
PubChem ID
31953
Melting Point
280 °C
Appearance
Yellow or dark yellow powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
2'-(4-Hydroxyphenyl)-5-(4-methyl-1-piperazinyl)-2,5'-bi(1H-benzimidazole)trihydrochloride, 2-[2-(4-Hydroxyphenyl)-6-benzimidazoyl]-6-(1-methyl-4-piperazyl)benzimidazoletrihydrochloride, BBIH, BXI-72
CAS Number
23491-45-4
Purity
≥ 98% (HPLC)
Molecular Formula
C25H24N6O·3HCl
Molecular Weight
533.88
MDL Number
MFCD00012679
PubChem ID
31953
Melting Point
280 °C
Appearance
Yellow or dark yellow powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Bisbenzimide H 33258 is widely utilized in research focused on:

  • Nucleic Acid Staining: This compound is commonly used in fluorescence microscopy to stain DNA, allowing researchers to visualize cellular structures and processes. Its ability to bind specifically to DNA makes it invaluable in genetic studies.
  • Cell Cycle Analysis: In flow cytometry, it helps in assessing the cell cycle phases by staining DNA content. This application is crucial for cancer research and understanding cell proliferation.
  • Histological Studies: It is employed in histology for tissue section staining, providing clear differentiation of cellular components. This aids pathologists in diagnosing diseases.
  • Drug Discovery: The compound is used in screening assays to evaluate the effects of new drugs on DNA synthesis and repair mechanisms, which is essential in developing cancer therapies.
  • Environmental Monitoring: Bisbenzimide H 33258 can be applied in studies assessing the impact of pollutants on genetic material in various organisms, contributing to environmental safety assessments.

Citations