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Catalog Number:
41764
CAS Number:
4333-21-5
Phenylthiohydantoin-proline
Purity:
≥ 98% (HPLC)
Synonym(s):
PTH-proline
Documents
$68.20 /100MG
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Product Information

Phenylthiohydantoin-proline is a unique compound that serves as a valuable tool in various biochemical applications, particularly in the field of peptide synthesis and analysis. This compound is recognized for its ability to form stable derivatives with amino acids, making it an essential reagent in the identification and characterization of peptides. Its distinctive structure allows for efficient labeling and separation processes, which are crucial in proteomics and analytical chemistry. Researchers often utilize Phenylthiohydantoin-proline in high-performance liquid chromatography (HPLC) to enhance the resolution of peptide mixtures, thereby facilitating more accurate analyses.

Additionally, this compound's properties make it an attractive choice for pharmaceutical research, where it can be employed in the development of novel therapeutic agents. Its compatibility with various reaction conditions and its ability to stabilize reactive intermediates contribute to its versatility in synthetic pathways. By incorporating Phenylthiohydantoin-proline into their workflows, researchers can achieve improved yields and purities in their chemical processes, ultimately leading to more efficient and effective outcomes in their studies.

Synonyms
PTH-proline
CAS Number
4333-21-5
Purity
≥ 98% (HPLC)
Molecular Formula
C12H12N2OS
Molecular Weight
232.3
MDL Number
MFCD00056895
PubChem ID
100798
Melting Point
177 - 181 °C
Appearance
White to off-white powder
Conditions
Store at RT
General Information
Synonyms
PTH-proline
CAS Number
4333-21-5
Purity
≥ 98% (HPLC)
Molecular Formula
C12H12N2OS
Molecular Weight
232.3
MDL Number
MFCD00056895
PubChem ID
100798
Melting Point
177 - 181 °C
Appearance
White to off-white powder
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Phenylthiohydantoin-proline is widely utilized in research focused on:

  • Protein Sequencing: This compound is instrumental in the Edman degradation method, a technique used to determine the amino acid sequence of proteins. It enhances the accuracy of sequencing, making it invaluable in biochemistry and molecular biology.
  • Peptide Synthesis: It plays a crucial role in synthesizing peptides, which are essential for various biological functions and applications in pharmaceuticals. Its ability to form stable derivatives aids in the development of new therapeutic agents.
  • Drug Development: Researchers leverage its properties to create and test new drugs, particularly in the field of oncology. Its unique structure allows for modifications that can lead to more effective treatments.
  • Biochemical Assays: The compound is used in various assays to study enzyme activity and protein interactions, providing insights into metabolic pathways and disease mechanisms.
  • Analytical Chemistry: It serves as a reagent in analytical techniques, helping to identify and quantify amino acids in complex mixtures, which is crucial for quality control in food and pharmaceutical industries.

Citations