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Catalog Number:
42373
CAS Number:
431-47-0
Methyl trifluoroacetate
Purity:
≥ 99% (GC)
Synonym(s):
Trifluoroacetic acid methyl ester
Hazmat
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Product Information

Methyl trifluoroacetate is a versatile chemical compound widely utilized in organic synthesis and various industrial applications. Known for its trifluoromethyl group, this compound serves as an essential building block in the production of pharmaceuticals, agrochemicals, and specialty chemicals. Its unique properties, including high reactivity and stability, make it particularly valuable in the synthesis of fluorinated compounds, which are increasingly important in modern chemistry due to their enhanced biological activity and environmental stability. Researchers often leverage methyl trifluoroacetate in the development of innovative drug formulations and agrochemical products, benefiting from its ability to introduce trifluoromethyl groups into target molecules, thereby improving their efficacy and performance.

In addition to its applications in pharmaceuticals and agrochemicals, methyl trifluoroacetate is also employed in the production of polymers and as a solvent in various chemical reactions. Its low toxicity and favorable handling characteristics make it an attractive choice for both laboratory and industrial settings. By incorporating methyl trifluoroacetate into their processes, professionals can achieve higher yields and improved product characteristics, positioning themselves at the forefront of chemical innovation.

Synonyms
Trifluoroacetic acid methyl ester
CAS Number
431-47-0
Purity
≥ 99% (GC)
Molecular Formula
C3H3F3O2
Molecular Weight
0
MDL Number
MFCD00000417
PubChem ID
9893
Melting Point
-78 °C
Density
1.29
Appearance
Colorless transparent liquid
Boiling Point
43 °C
Refractive Index
n20D 1.29
Conditions
Store at RT
General Information
Synonyms
Trifluoroacetic acid methyl ester
CAS Number
431-47-0
Purity
≥ 99% (GC)
Molecular Formula
C3H3F3O2
Molecular Weight
0
MDL Number
MFCD00000417
PubChem ID
9893
Melting Point
-78 °C
Density
1.29
Appearance
Colorless transparent liquid
Boiling Point
43 °C
Refractive Index
n20D 1.29
Conditions
Store at RT
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Methyl trifluoroacetate is widely utilized in research focused on:

  • Synthesis of Fluorinated Compounds: It serves as a key reagent in the synthesis of various fluorinated organic compounds, which are valuable in pharmaceuticals and agrochemicals.
  • Intermediate in Drug Development: This compound acts as an important intermediate in the production of drugs, particularly those requiring fluorine for enhanced biological activity and metabolic stability.
  • Analytical Chemistry: Methyl trifluoroacetate is used in analytical methods, such as gas chromatography, to derivatize alcohols and amines, improving detection sensitivity.
  • Polymer Chemistry: It is employed in the synthesis of fluorinated polymers, which exhibit unique properties like chemical resistance and thermal stability, beneficial in coatings and materials science.
  • Environmental Applications: The compound is explored for its potential in developing environmentally friendly solvents and reagents, aligning with green chemistry principles.

Citations