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Catalog Number:
31529
CAS Number:
429-41-4
Tetrabutylammonium fluoride solution, 1.0 M in THF
Purity:
0.95 - 1.1 mol/L (Assay)
Synonym(s):
TBAF solution
Hazmat
Documents
$20.00 /25ML
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Product Information

Tetrabutylammonium fluoride solution, 1.0 M in THF, is a versatile reagent widely utilized in organic synthesis and various chemical applications. This compound serves as a strong fluoride source, making it essential for reactions requiring fluoride ions, such as nucleophilic substitutions and deprotection of silyl ethers. Its solubility in tetrahydrofuran (THF) enhances its utility in polar aprotic solvent systems, allowing for efficient reaction conditions in both laboratory and industrial settings. Researchers appreciate its stability and ease of handling, which facilitate precise control over reaction parameters.

In addition to its role in organic synthesis, Tetrabutylammonium fluoride is also employed in the preparation of fluorinated compounds, contributing to the development of pharmaceuticals and agrochemicals. Its unique properties allow for selective fluorination, which can improve the biological activity of drug candidates. With its high purity and reliable performance, this reagent is an excellent choice for chemists seeking to enhance their synthetic methodologies and achieve superior results in their research and development projects.

Synonyms
TBAF solution
CAS Number
429-41-4
Purity
0.95 - 1.1 mol/L (Assay)
Molecular Formula
C16H36FN
Molecular Weight
261.46
MDL Number
MFCD00011747
PubChem ID
2724141
Density
0.9 - 1.0 g/mL
Appearance
Clear faint yellow to yellow or clear colorless liquid
Conditions
Store at 2 - 8 °C
General Information
Synonyms
TBAF solution
CAS Number
429-41-4
Purity
0.95 - 1.1 mol/L (Assay)
Molecular Formula
C16H36FN
Molecular Weight
261.46
MDL Number
MFCD00011747
PubChem ID
2724141
Density
0.9 - 1.0 g/mL
Appearance
Clear faint yellow to yellow or clear colorless liquid
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Tetrabutylammonium fluoride solution, 1.0 M in THF is widely utilized in research focused on:

  • Organic Synthesis: This compound serves as a strong nucleophile in various organic reactions, facilitating the synthesis of complex molecules, particularly in the development of pharmaceuticals and agrochemicals.
  • Ion Exchange Processes: It is effective in ion exchange applications, particularly in the preparation of ionic liquids, which are used in electrochemistry and catalysis.
  • Fluorination Reactions: The solution is commonly employed for the selective fluorination of organic substrates, enhancing the properties of compounds in medicinal chemistry.
  • Polymer Chemistry: It plays a crucial role in modifying polymer properties, making it valuable in the production of advanced materials with tailored characteristics.
  • Analytical Chemistry: This compound is used in various analytical techniques, including NMR spectroscopy, to study molecular structures and dynamics, providing insights into chemical behavior.

Citations