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Catalog Number:
38482
CAS Number:
31282-04-9
Hygromycin B from Streptomyces hygroscopicus powder
Grade:
suitable for cell culture, suitable for insect cell culture
Purity:
≥ 90% (HPLC)
Hazmat
Documents
$61.29 /250MG
Pack Size Availability Price
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Product Information

Hygromycin B from Streptomyces hygroscopicus powder is a potent antibiotic known for its effectiveness against a wide range of Gram-negative bacteria and some Gram-positive strains. This compound is particularly valued in microbiological research and pharmaceutical applications due to its ability to inhibit protein synthesis, making it an essential tool for studying bacterial genetics and function. Researchers often utilize Hygromycin B in the selection of genetically modified organisms, as it provides a reliable means to ensure that only cells expressing the resistance gene survive under selective pressure.

In addition to its applications in molecular biology, Hygromycin B has shown promise in agricultural settings, particularly in the development of transgenic plants. Its unique mechanism of action allows for the effective selection of transformed plant cells, facilitating advancements in crop improvement and biotechnology. With its broad-spectrum activity and specific targeting of bacterial ribosomes, Hygromycin B stands out as a versatile agent in both laboratory and field applications, making it an invaluable resource for researchers and industry professionals alike.

CAS Number
31282-04-9
Purity
≥ 90% (HPLC)
Grade
suitable for cell culture, suitable for insect cell culture
Molecular Formula
C20H37N3O13
Molecular Weight
527.52
MDL Number
MFCD06795479
PubChem ID
3659
Appearance
White to off-white powder
Optical Rotation
[a]20D = 18 - 23 °
Conditions
Store at 0 - 8 °C
General Information
CAS Number
31282-04-9
Purity
≥ 90% (HPLC)
Grade
suitable for cell culture, suitable for insect cell culture
Molecular Formula
C20H37N3O13
Molecular Weight
527.52
MDL Number
MFCD06795479
PubChem ID
3659
Appearance
White to off-white powder
Optical Rotation
[a]20D = 18 - 23 °
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Hygromycin B from Streptomyces hygroscopicus powder is widely utilized in research focused on:

  • Antibiotic Research: It serves as a potent antibiotic, particularly effective against a range of Gram-negative bacteria, making it invaluable in microbiological studies and antibiotic resistance research.
  • Cell Culture Applications: Researchers use it as a selective agent in cell culture to maintain and select genetically modified cells, ensuring that only those expressing the hygromycin resistance gene survive.
  • Gene Expression Studies: It aids in the study of gene expression by allowing scientists to create stable cell lines that express specific genes, facilitating the investigation of gene function and regulation.
  • Plant Transformation: In plant biotechnology, hygromycin B is employed as a selection marker in the transformation of plants, helping researchers to identify successfully transformed plants in genetic engineering projects.
  • Pharmaceutical Development: It is used in the development of new antibiotics and therapeutic agents, providing a basis for testing the efficacy of new compounds against resistant bacterial strains.

Citations