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Catalog Number:
22127
CAS Number:
23541-50-6
Daunorubicin hydrochloride
Purity:
≥ 98% (N)
Synonym(s):
Hydroxydaunorubicin hydrochloride, Daunomycin hydrochloride
Hazmat
Documents
$255.48 /20MG
Pack Size Availability Price
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Product Information

Daunorubicin hydrochloride is a potent anthracycline antibiotic widely utilized in oncology for its effective anti-cancer properties. This compound is primarily used in the treatment of various hematological malignancies, including acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Its mechanism of action involves intercalating into DNA, thereby inhibiting DNA and RNA synthesis, which ultimately leads to cancer cell death. Researchers and healthcare professionals appreciate Daunorubicin hydrochloride for its ability to enhance the efficacy of combination chemotherapy regimens, making it a critical component in modern cancer treatment protocols.

In addition to its therapeutic applications, Daunorubicin hydrochloride is also being explored in research settings for its potential use in targeted drug delivery systems and as a model compound for developing new anti-cancer agents. Its unique structural features allow for modifications that can improve its selectivity and reduce side effects, making it a valuable compound for ongoing studies in drug development. With its established role in cancer therapy and ongoing research into its applications, Daunorubicin hydrochloride remains a significant focus for both clinicians and researchers in the fight against cancer.

Synonyms
Hydroxydaunorubicin hydrochloride, Daunomycin hydrochloride
CAS Number
23541-50-6
Purity
≥ 98% (N)
Molecular Formula
C27H29NO10·HCl
Molecular Weight
563.98
MDL Number
MFCD04974507
PubChem ID
21864425
Melting Point
167 °C(dec.)
Appearance
Orange to red powder to crystal
Optical Rotation
250 - 275 ° (C=0.15, MeOH)
Conditions
Store at 0 - 8 °C
General Information
Synonyms
Hydroxydaunorubicin hydrochloride, Daunomycin hydrochloride
CAS Number
23541-50-6
Purity
≥ 98% (N)
Molecular Formula
C27H29NO10·HCl
Molecular Weight
563.98
MDL Number
MFCD04974507
PubChem ID
21864425
Melting Point
167 °C(dec.)
Appearance
Orange to red powder to crystal
Optical Rotation
250 - 275 ° (C=0.15, MeOH)
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Daunorubicin hydrochloride is widely utilized in research focused on:

  • Cancer Treatment: This compound is primarily used in chemotherapy for treating certain types of leukemia, such as acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). Its ability to intercalate DNA helps inhibit cancer cell growth.
  • Combination Therapy: Often used in combination with other chemotherapeutic agents, it enhances the overall effectiveness of treatment regimens, allowing for more comprehensive cancer management.
  • Research in Drug Resistance: Scientists study daunorubicin hydrochloride to understand mechanisms of drug resistance in cancer cells, which can lead to the development of more effective therapies.
  • Cardiotoxicity Studies: Researchers investigate the cardiotoxic effects of this compound to develop strategies that mitigate heart-related side effects in patients undergoing chemotherapy.
  • Formulation Development: It is used in the formulation of liposomal drugs, which can improve the delivery and efficacy of the drug while reducing side effects, making treatments safer for patients.

Citations