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Catalog Number:
32310
CAS Number:
7355-18-2
Methyl 1,2,3,4-tetra-O-acetyl-ॆ-D-glucuronate
Purity:
≥ 99%
Synonym(s):
(2S,3R,4S,5S,6S)-6-(Methoxycarbonyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate, 1,2,3,4-Tetra-O-acetyl-β-D-glucopyranuronic acid methyl ester
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Product Information

Methyl 1,2,3,4-tetra-O-acetyl-b-D-glucuronate is a versatile compound widely recognized for its applications in the fields of biochemistry and pharmaceuticals. This acetylated derivative of glucuronic acid is particularly valuable in the synthesis of glycosides and other carbohydrate derivatives, making it an essential building block for researchers engaged in carbohydrate chemistry. Its unique structure allows for enhanced solubility and stability, which is crucial for various applications, including drug formulation and delivery systems.

In addition to its role in synthetic chemistry, Methyl 1,2,3,4-tetra-O-acetyl-b-D-glucuronate is also utilized in the development of glycoproteins and polysaccharides, contributing to advancements in drug design and therapeutic agents. Its ability to modify biological molecules enhances their efficacy and bioavailability, making it a preferred choice among professionals in pharmaceutical research and development. With its broad range of applications, this compound stands out for its practicality and effectiveness in enhancing the performance of various biochemical products.

Synonyms
(2S,3R,4S,5S,6S)-6-(Methoxycarbonyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate, 1,2,3,4-Tetra-O-acetyl-β-D-glucopyranuronic acid methyl ester
CAS Number
7355-18-2
Purity
≥ 99%
Molecular Formula
C15H20O11
Molecular Weight
376.31
MDL Number
MFCD00069834
PubChem ID
226478
Appearance
White to light brown powder
Optical Rotation
[a]D20 = 7 - 11 ° (C=1 in CHCl3)
Conditions
Store at 2-8 °C
General Information
Synonyms
(2S,3R,4S,5S,6S)-6-(Methoxycarbonyl)tetrahydro-2H-pyran-2,3,4,5-tetrayl tetraacetate, 1,2,3,4-Tetra-O-acetyl-β-D-glucopyranuronic acid methyl ester
CAS Number
7355-18-2
Purity
≥ 99%
Molecular Formula
C15H20O11
Molecular Weight
376.31
MDL Number
MFCD00069834
PubChem ID
226478
Appearance
White to light brown powder
Optical Rotation
[a]D20 = 7 - 11 ° (C=1 in CHCl3)
Conditions
Store at 2-8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Methyl 1,2,3,4-tetra-O-acetyl-b-D-glucuronate is widely utilized in research focused on:

  • Synthesis of Glycosides: This compound serves as a key intermediate in the synthesis of various glycosides, which are important for drug development and biochemical research.
  • Drug Delivery Systems: Its acetylated form enhances solubility and stability, making it useful in formulating drug delivery systems that require improved bioavailability.
  • Biochemical Assays: Researchers utilize this compound in assays to study enzyme activity related to glycosylation processes, aiding in the understanding of metabolic pathways.
  • Natural Product Chemistry: It is employed in the structural modification of natural products, allowing chemists to explore new therapeutic agents derived from plant sources.
  • Analytical Chemistry: The compound is used in various analytical techniques, including chromatography, to separate and identify complex mixtures of carbohydrates.

Citations