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Catalog Number:
42196
CAS Number:
19542-67-7
BAY 11-7082
Purity:
≥ 98% (HPLC)
Synonym(s):
(E-3-Tosylacrylonitrile, (E-3-(p-Toluenesulfonyl)acrylonitrile
Documents
$46.77 /100MG
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Product Information

BAY 11-7082 is a potent and selective inhibitor of the NF-κB signaling pathway, making it a valuable tool in both research and therapeutic applications. This compound has garnered attention for its ability to modulate inflammatory responses and has been utilized in studies exploring various diseases, including cancer and autoimmune disorders. Its unique sulfonylprop-2-enenitrile structure contributes to its efficacy in inhibiting the activation of NF-κB, which is crucial in regulating immune responses and cell survival. Researchers have found BAY 11-7082 particularly useful in in vitro and in vivo studies aimed at understanding the mechanisms of inflammation and tumorigenesis.

In addition to its applications in basic research, BAY 11-7082 holds promise in the development of novel therapeutic strategies. Its ability to selectively inhibit NF-κB provides a pathway for potential treatments that target inflammatory diseases and cancer. The compound's effectiveness in reducing cytokine production and promoting apoptosis in cancer cells highlights its relevance in the pharmaceutical industry. With its growing recognition, BAY 11-7082 is positioned as a significant compound for researchers and industry professionals seeking to explore innovative solutions in disease management.

Synonyms
(E-3-Tosylacrylonitrile, (E-3-(p-Toluenesulfonyl)acrylonitrile
CAS Number
19542-67-7
Purity
≥ 98% (HPLC)
Molecular Formula
C10H9NO2S
Molecular Weight
207.25
MDL Number
MFCD00712162
PubChem ID
2301
Melting Point
132 - 136 °C
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(E-3-Tosylacrylonitrile, (E-3-(p-Toluenesulfonyl)acrylonitrile
CAS Number
19542-67-7
Purity
≥ 98% (HPLC)
Molecular Formula
C10H9NO2S
Molecular Weight
207.25
MDL Number
MFCD00712162
PubChem ID
2301
Melting Point
132 - 136 °C
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

BAY 11-7082 is widely utilized in research focused on:

  • Anti-inflammatory Research: This compound is known for its ability to inhibit NF-kB activation, making it valuable in studies aimed at understanding and treating inflammatory diseases.
  • Cancer Therapy Development: Researchers explore its potential in cancer treatment due to its role in inducing apoptosis in various cancer cell lines, providing a pathway for developing new therapeutic strategies.
  • Neuroscience Applications: It is used in neuroprotective studies, particularly in models of neurodegenerative diseases, helping to identify mechanisms that could lead to new treatments.
  • Cardiovascular Research: The compound's effects on cellular signaling pathways are studied to understand its implications in heart disease, potentially leading to novel cardiovascular therapies.
  • Drug Development: Its unique properties make it a candidate for formulating new drugs, especially those targeting inflammatory and autoimmune conditions, offering advantages over traditional treatments.

Citations