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Catalog Number:
42195
CAS Number:
196309-76-9
BAY 11-7085
Purity:
≥ 98% (HPLC)
Synonym(s):
(E-3-(4-tert-Butylphenylsulfonyl)acrylonitrile
Documents
$134.70 /10MG
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Product Information

BAY 11-7085 is a potent and selective inhibitor of the NF-kB signaling pathway, making it a valuable tool in both research and therapeutic applications. This compound is recognized for its ability to modulate inflammatory responses and has been extensively studied for its potential in cancer research, where it may help in reducing tumor growth and metastasis. Researchers have utilized BAY 11-7085 to explore its effects on various cell lines, demonstrating its efficacy in inhibiting cell proliferation and inducing apoptosis in cancer cells. Additionally, its role in neuroprotection and as a potential treatment for neurodegenerative diseases has garnered attention, highlighting its versatility in biomedical research.

With its unique sulfonylprop-2-enenitrile structure, BAY 11-7085 offers advantages over other NF-kB inhibitors, such as enhanced specificity and reduced off-target effects. This makes it an ideal candidate for studies focused on inflammatory diseases, autoimmune disorders, and cancer therapy. Its ability to effectively block NF-kB activation positions BAY 11-7085 as a crucial compound for researchers aiming to develop targeted therapies and understand the underlying mechanisms of disease.

Synonyms
(E-3-(4-tert-Butylphenylsulfonyl)acrylonitrile
CAS Number
196309-76-9
Purity
≥ 98% (HPLC)
Molecular Formula
C13H15NO2S
Molecular Weight
249.33
MDL Number
MFCD01862602
PubChem ID
2302
Melting Point
82 - 86 °C
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
General Information
Synonyms
(E-3-(4-tert-Butylphenylsulfonyl)acrylonitrile
CAS Number
196309-76-9
Purity
≥ 98% (HPLC)
Molecular Formula
C13H15NO2S
Molecular Weight
249.33
MDL Number
MFCD01862602
PubChem ID
2302
Melting Point
82 - 86 °C
Appearance
White to off-white powder
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

BAY 11-7085 is widely utilized in research focused on:

  • Inflammation Studies: This compound is known for its ability to inhibit NF-kB activation, making it valuable in studies aimed at understanding inflammatory diseases and potential therapeutic interventions.
  • Cancer Research: Researchers use BAY 11-7085 to explore its effects on cancer cell proliferation and survival, particularly in studies targeting tumor growth and metastasis.
  • Neuroscience Applications: The compound has been investigated for its neuroprotective properties, offering insights into treatments for neurodegenerative diseases.
  • Drug Development: Its unique mechanism of action provides a basis for developing new anti-inflammatory and anticancer drugs, helping to address the limitations of existing therapies.
  • Cell Signaling Pathway Analysis: BAY 11-7085 is used in experiments to dissect various signaling pathways, aiding in the understanding of cellular responses to stress and injury.

Citations