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Catalog Number:
38838
CAS Number:
54-62-6
Aminopterin
Grade:
Suitable for cell culture
Purity:
≥ 97% (TLC)
Synonym(s):
4-Amino-Pga, 4-Aminofolic acid, 4-Aminopteroyl-L-glutamic acid
Hazmat
Documents
$88.33 /10MG
Pack Size Availability Price
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Product Information
Synonyms
4-Amino-Pga, 4-Aminofolic acid, 4-Aminopteroyl-L-glutamic acid
CAS Number
54-62-6
Purity
≥ 97% (TLC)
Grade
Suitable for cell culture
Molecular Formula
C19H20N8O5
Molecular Weight
0
MDL Number
MFCD00036692
PubChem ID
2154
Melting Point
221 - 223 °C
Appearance
White to amber crystalline powder
Conditions
Store at 0 - 10 °C
General Information
Synonyms
4-Amino-Pga, 4-Aminofolic acid, 4-Aminopteroyl-L-glutamic acid
CAS Number
54-62-6
Purity
≥ 97% (TLC)
Grade
Suitable for cell culture
Molecular Formula
C19H20N8O5
Molecular Weight
0
MDL Number
MFCD00036692
PubChem ID
2154
Melting Point
221 - 223 °C
Appearance
White to amber crystalline powder
Conditions
Store at 0 - 10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Aminopterin is widely utilized in research focused on:

  • Cancer Treatment: It is used as a chemotherapy agent, particularly in the treatment of leukemia, where it helps inhibit cell division and growth of cancer cells.
  • Autoimmune Disease Research: Aminopterin plays a role in studying autoimmune diseases by suppressing the immune response, allowing researchers to explore therapeutic options.
  • Cell Culture Studies: In laboratory settings, it is employed to select for cells that are resistant to antifolates, aiding in the development of new drugs and therapies.
  • Genetic Research: It is used in genetic studies to induce mutations in model organisms, providing insights into gene function and disease mechanisms.
  • Pharmaceutical Development: The compound is valuable in the development of new antifolate drugs, offering a basis for creating more effective treatments with fewer side effects.

Citations