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Catalog Number:
38283
CAS Number:
50-35-1
±)-Thalidomide
Purity:
≥ 98% (HPLC)
Synonym(s):
N-(2,6-Dioxo-3-piperidinyl)phthalimide
Hazmat
Documents
$189.58 /1G
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Product Information

(±)-Thalidomide is a compound renowned for its multifaceted applications in the pharmaceutical industry, particularly in the treatment of various conditions such as multiple myeloma and leprosy. Originally developed as a sedative, its unique properties have led to its repurposing as an immunomodulatory agent, making it invaluable in managing inflammatory diseases and certain cancers. Researchers and healthcare professionals appreciate its ability to inhibit angiogenesis and modulate immune responses, which is crucial in developing targeted therapies.

In addition to its therapeutic uses, (±)-Thalidomide has garnered attention for its role in clinical research, particularly in understanding the mechanisms of drug action and the development of novel treatment protocols. Its effectiveness in combination therapies further enhances its appeal, providing a synergistic approach to patient care. With a well-documented safety profile when used appropriately, (±)-Thalidomide continues to be a significant compound in modern medicine, offering hope and improved outcomes for patients worldwide.

Synonyms
N-(2,6-Dioxo-3-piperidinyl)phthalimide
CAS Number
50-35-1
Purity
≥ 98% (HPLC)
Molecular Formula
C13H10N2O4
Molecular Weight
258.23
MDL Number
MFCD00153873
PubChem ID
5426
Melting Point
275 - 277 ?C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
General Information
Synonyms
N-(2,6-Dioxo-3-piperidinyl)phthalimide
CAS Number
50-35-1
Purity
≥ 98% (HPLC)
Molecular Formula
C13H10N2O4
Molecular Weight
258.23
MDL Number
MFCD00153873
PubChem ID
5426
Melting Point
275 - 277 ?C
Appearance
White to almost white powder to crystal
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

(±)-Thalidomide is widely utilized in research focused on

  • Multiple Myeloma Treatment: This compound is approved for treating multiple myeloma, a type of blood cancer. Its ability to inhibit tumor growth and modulate the immune system makes it a valuable option for patients.
  • Leprosy Management: Thalidomide is effective in treating complications of leprosy, particularly erythema nodosum leprosum, providing relief from painful skin lesions and inflammation.
  • Anti-Inflammatory Applications: Due to its immunomodulatory properties, it is used in treating various inflammatory conditions, including Crohn's disease and ulcerative colitis, offering an alternative for patients who do not respond to conventional therapies.
  • Research in Angiogenesis: Thalidomide is studied for its role in inhibiting angiogenesis, the formation of new blood vessels, which is crucial in cancer progression and other diseases, making it a key focus in cancer research.
  • Potential in Autoimmune Disorders: Ongoing research is exploring its use in autoimmune diseases like lupus and rheumatoid arthritis, where it may help modulate the immune response and reduce symptoms.

Citations