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Catalog Number:
38182
CAS Number:
19171-19-8
Pomalidomide
Purity:
≥ 98% (HPLC)
Synonym(s):
3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide, 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline,3-amino-N-(2,6-dioxo-3-piperidyl)phthalamide
Documents
$18.53 /25MG
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Product Information

Pomalidomide is a potent immunomodulatory drug primarily used in the treatment of multiple myeloma, particularly in patients who have received prior therapies. This compound functions by enhancing the immune response against cancer cells and inhibiting the growth of tumor cells. Its unique structure allows it to modulate various cytokines and promote apoptosis in malignant cells, making it a valuable option in oncology. Pomalidomide is recognized for its effectiveness in combination therapies, often used alongside dexamethasone to improve patient outcomes.

In addition to its applications in cancer treatment, Pomalidomide is being explored for potential uses in other conditions, such as autoimmune diseases and certain viral infections, due to its ability to modulate immune responses. Researchers appreciate its favorable pharmacokinetic profile, which allows for flexible dosing regimens. With ongoing studies, Pomalidomide continues to demonstrate promise in expanding treatment options for challenging diseases, making it a significant compound in modern therapeutic strategies.

Synonyms
3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide, 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline,3-amino-N-(2,6-dioxo-3-piperidyl)phthalamide
CAS Number
19171-19-8
Purity
≥ 98% (HPLC)
Molecular Formula
C13H11N3O4
Molecular Weight
273.25
MDL Number
MFCD12756407
PubChem ID
134780
Melting Point
312 - 314 °C (dec.)
Appearance
White to yellow to green powder to crystaline
Conditions
Store at 2 - 8 °C
General Information
Synonyms
3-Amino-N-(2,6-dioxo-3-piperidyl)phthalimide, 1,3-dioxo-2-(2,6-dioxopiperidin-3-yl)-4-aminoisoindoline,3-amino-N-(2,6-dioxo-3-piperidyl)phthalamide
CAS Number
19171-19-8
Purity
≥ 98% (HPLC)
Molecular Formula
C13H11N3O4
Molecular Weight
273.25
MDL Number
MFCD12756407
PubChem ID
134780
Melting Point
312 - 314 °C (dec.)
Appearance
White to yellow to green powder to crystaline
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Pomalidomide is widely utilized in research focused on:

  • Oncology Treatments: It is primarily used in the treatment of multiple myeloma, providing an effective option for patients who have not responded to other therapies.
  • Immunomodulation: Pomalidomide enhances immune responses, making it valuable in developing therapies that boost the body's ability to fight cancer.
  • Clinical Trials: Researchers are actively investigating its potential in combination therapies, exploring how it can be paired with other drugs to improve patient outcomes.
  • Hematology: Beyond cancer, it is being studied for its effects on various blood disorders, showcasing its versatility in treating different conditions.
  • Research on Mechanisms of Action: Scientists are examining how pomalidomide works at the molecular level, which could lead to the discovery of new therapeutic targets and strategies.

Citations