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Catalog Number:
38172
CAS Number:
58-33-3
Promethazine hydrochloride
Purity:
≥ 99% (Assay on dried basis)
Synonym(s):
10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride
Hazmat
Documents
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Product Information

Promethazine hydrochloride is a versatile pharmaceutical compound recognized for its antihistaminic properties, making it invaluable in various medical applications. This compound is primarily used to alleviate allergy symptoms, such as runny nose, sneezing, and itching, and is also effective in preventing motion sickness and treating nausea and vomiting. Its sedative effects make it a common choice for preoperative sedation and as a sleep aid, providing comfort to patients undergoing medical procedures.

In addition to its therapeutic uses, Promethazine hydrochloride is utilized in veterinary medicine to manage similar conditions in animals, showcasing its broad applicability across species. Researchers appreciate its role in clinical studies, particularly in understanding drug interactions and effects on the central nervous system. The compound's unique ability to cross the blood-brain barrier enhances its efficacy in treating conditions requiring central nervous system intervention. With its established safety profile and diverse applications, Promethazine hydrochloride remains a staple in both human and veterinary medicine.

Synonyms
10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride
CAS Number
58-33-3
Purity
≥ 99% (Assay on dried basis)
Molecular Formula
C17H20N2S·HCl
Molecular Weight
320.88
MDL Number
MFCD00012652
PubChem ID
6014
Appearance
White or almost white powder or particles
Conditions
Store at 0 - 8 °C
General Information
Synonyms
10-[2-(Dimethylamino)propyl]phenothiazine hydrochloride
CAS Number
58-33-3
Purity
≥ 99% (Assay on dried basis)
Molecular Formula
C17H20N2S·HCl
Molecular Weight
320.88
MDL Number
MFCD00012652
PubChem ID
6014
Appearance
White or almost white powder or particles
Conditions
Store at 0 - 8 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Promethazine hydrochloride is widely utilized in research focused on:

  • Allergy Relief: Commonly used in the treatment of allergic reactions, it helps alleviate symptoms such as itching, runny nose, and hives, making it essential in allergy clinics and hospitals.
  • Motion Sickness Prevention: This compound is effective in preventing nausea and vomiting associated with motion sickness, making it valuable for travel-related industries, such as cruise lines and airlines.
  • Preoperative Sedation: In medical settings, it is often administered to patients prior to surgery to provide sedation and reduce anxiety, enhancing patient comfort and cooperation.
  • Sleep Aid: Due to its sedative properties, it is used in some formulations to help individuals with insomnia, providing a non-habit forming option for sleep disturbances.
  • Antiemetic Use: It is effective in controlling nausea and vomiting caused by chemotherapy, making it a critical component in oncology treatment protocols.

Citations