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Catalog Number:
38056
CAS Number:
50924-49-7
Mizoribine
Purity:
≥ 98% (HPLC)
Synonym(s):
1-(ß-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide
Documents
$201.60 /50MG
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Product Information

Mizoribine is a potent immunosuppressive agent primarily utilized in the field of organ transplantation and autoimmune diseases. This compound functions by selectively inhibiting lymphocyte proliferation, making it invaluable in preventing organ rejection post-transplantation and managing conditions such as rheumatoid arthritis and lupus. Its unique mechanism of action allows for effective modulation of the immune response, providing a critical therapeutic option for patients requiring long-term immunosuppression.

In addition to its clinical applications, Mizoribine has garnered interest in research settings, particularly in studies focused on cellular immunity and the development of novel immunotherapies. Its favorable safety profile compared to other immunosuppressants enhances its appeal among healthcare professionals. Mizoribine's ability to maintain a balance between efficacy and safety positions it as a preferred choice in various therapeutic regimens, ensuring better patient outcomes and improved quality of life.

Synonyms
1-(ß-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide
CAS Number
50924-49-7
Purity
≥ 98% (HPLC)
Molecular Formula
C9H13N3O6
Molecular Weight
259.22
MDL Number
MFCD00057221
PubChem ID
4213
Melting Point
198 °C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = -25 to -27 ° (C=2 in water)
Conditions
Store at 2 - 8 °C
General Information
Synonyms
1-(ß-D-Ribofuranosyl)-5-hydroxyimidazole-4-carboxamide
CAS Number
50924-49-7
Purity
≥ 98% (HPLC)
Molecular Formula
C9H13N3O6
Molecular Weight
259.22
MDL Number
MFCD00057221
PubChem ID
4213
Melting Point
198 °C (dec.)
Appearance
White to almost white powder to crystal
Optical Rotation
[a]D20 = -25 to -27 ° (C=2 in water)
Conditions
Store at 2 - 8 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Mizoribine is widely utilized in research focused on:

  • Immunosuppressive Therapy: This compound is primarily used in transplant medicine to prevent organ rejection by suppressing the immune response, making it essential for patients undergoing kidney transplants.
  • Autoimmune Disease Treatment: Mizoribine is effective in managing conditions like rheumatoid arthritis and lupus, providing relief by modulating the immune system's activity.
  • Research in Pharmacology: It serves as a valuable tool in pharmacological studies to understand immune responses and the development of new immunosuppressive agents.
  • Combination Therapies: Often used in conjunction with other immunosuppressants, it enhances treatment efficacy while potentially reducing side effects compared to higher doses of single agents.
  • Investigational Studies: Mizoribine is being explored in clinical trials for various conditions, including certain cancers, where immune modulation may improve treatment outcomes.

Citations