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Catalog Number:
37879
CAS Number:
153439-40-8
Fexofenadine hydrochloride
Grade:
Meets USP specification
Purity:
98 - 102% (Assay on anhydrous basis)
Synonym(s):
Terfenidine carboxylate hydrochloride, MDL 16455 hydrochloride
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Product Information

Fexofenadine hydrochloride is a potent antihistamine widely recognized for its effectiveness in alleviating allergy symptoms such as hay fever and urticaria. This compound operates by selectively blocking peripheral H1 receptors, thereby reducing the effects of histamine, which is responsible for allergic reactions. Its rapid onset of action and minimal sedative effects make it an ideal choice for individuals seeking relief without the drowsiness associated with many other antihistamines. Fexofenadine hydrochloride is particularly beneficial in clinical settings, where it is utilized in the management of allergic rhinitis and chronic idiopathic urticaria, providing patients with a reliable option for symptom control.

In addition to its therapeutic applications, Fexofenadine hydrochloride is also of interest in pharmaceutical research and development, where its unique properties can be leveraged to create innovative formulations. Its favorable safety profile and efficacy make it a valuable compound for researchers exploring new antihistamine therapies or combination treatments. With its established role in allergy management and ongoing research potential, Fexofenadine hydrochloride stands out as a significant compound in both clinical and research environments.

Synonyms
Terfenidine carboxylate hydrochloride, MDL 16455 hydrochloride
CAS Number
153439-40-8
Purity
98 - 102% (Assay on anhydrous basis)
Grade
Meets USP specification
Molecular Formula
C32H39NO4·HCl
Molecular Weight
538.13
MDL Number
MFCD00865710
PubChem ID
63002
Melting Point
148 - 150 °C (Lit.)
Appearance
White to off-white powder
Conditions
Store at ≤ - 4 °C
General Information
Synonyms
Terfenidine carboxylate hydrochloride, MDL 16455 hydrochloride
CAS Number
153439-40-8
Purity
98 - 102% (Assay on anhydrous basis)
Grade
Meets USP specification
Molecular Formula
C32H39NO4·HCl
Molecular Weight
538.13
MDL Number
MFCD00865710
PubChem ID
63002
Melting Point
148 - 150 °C (Lit.)
Appearance
White to off-white powder
Conditions
Store at ≤ - 4 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fexofenadine hydrochloride is widely utilized in research focused on:

  • Allergy Relief: Commonly used in the pharmaceutical industry, it serves as an effective antihistamine for treating allergic rhinitis and chronic urticaria, providing relief from symptoms like sneezing and itching.
  • Clinical Trials: Researchers employ this compound in clinical studies to evaluate its efficacy and safety compared to other antihistamines, helping to establish best practices in allergy treatment.
  • Formulation Development: In the development of new drug formulations, it is used to improve bioavailability and patient compliance, as it is available in various forms such as tablets and liquid.
  • Pharmacokinetics Research: The compound is studied for its pharmacokinetic properties, aiding researchers in understanding how the drug is absorbed, distributed, metabolized, and excreted in the body.
  • Combination Therapies: It is often explored in combination with other medications to enhance therapeutic effects, particularly in patients with multiple allergy symptoms, offering a more comprehensive treatment approach.

Citations