Discover the new Chem-Impex: Where innovation starts with a bond.

Catalog Number:
02102
CAS Number:
65-49-6
4-Aminosalicylic acid
Purity:
≥ 97% (Assay)
Synonym(s):
4-Amino-2-hydroxybenzoic acid, p-Aminosalicylic acid
Documents
$18.53 /25G
Pack Size Availability Price
Request Bulk Quote
Product Information

4-Aminosalicylic acid is a versatile compound widely recognized for its role in the pharmaceutical industry, particularly in the treatment of tuberculosis. This aromatic amino acid, also known as PAS or para-aminosalicylic acid, exhibits strong antibacterial properties, making it a valuable agent in combination therapies for multidrug-resistant strains of Mycobacterium tuberculosis. Its ability to inhibit folate synthesis in bacteria enhances its efficacy, providing a crucial alternative for patients who are resistant to first-line treatments.

In addition to its medicinal uses, 4-Aminosalicylic acid is utilized in various research applications, including studies on metabolic pathways and the development of new antimicrobial agents. Its unique chemical structure allows for modifications that can lead to the synthesis of novel derivatives with enhanced biological activity. Researchers and industry professionals benefit from its stability and compatibility with other compounds, making it an essential component in drug formulation and development.

Synonyms
4-Amino-2-hydroxybenzoic acid, p-Aminosalicylic acid
CAS Number
65-49-6
Purity
≥ 97% (Assay)
Molecular Formula
C7H7NO3
Molecular Weight
153.14
MDL Number
MFCD00007789
PubChem ID
4649
Melting Point
130 - 134 °C (Lit.)
Appearance
Off-white to brown crystalline powder
Conditions
Store at RT
General Information
Synonyms
4-Amino-2-hydroxybenzoic acid, p-Aminosalicylic acid
CAS Number
65-49-6
Purity
≥ 97% (Assay)
Molecular Formula
C7H7NO3
Molecular Weight
153.14
MDL Number
MFCD00007789
PubChem ID
4649
Melting Point
130 - 134 °C (Lit.)
Appearance
Off-white to brown crystalline powder
Conditions
Store at RT
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

4-Aminosalicylic acid is widely utilized in research focused on

  • Tuberculosis Treatment: This compound is primarily used as an anti-tubercular agent, especially in cases resistant to other medications. It helps in effectively reducing the bacterial load in patients.
  • Pharmaceutical Formulations: It is incorporated into various pharmaceutical products, enhancing the efficacy of treatments for respiratory diseases due to its ability to inhibit bacterial growth.
  • Research in Drug Development: Researchers use it as a model compound to study the mechanisms of drug resistance in bacteria, aiding in the development of new antibiotics.
  • Analytical Chemistry: 4-Aminosalicylic acid serves as a standard in analytical methods for quantifying similar compounds, ensuring accuracy in pharmaceutical quality control.
  • Biochemical Studies: It is utilized in biochemical assays to investigate metabolic pathways, providing insights into cellular processes and potential therapeutic targets.

Citations