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Catalog Number:
41977
CAS Number:
108964-32-5
Fura 2-AM
Grade:
suitable for Hematology & Histology
Purity:
≥ 95% (HPLC)
Synonym(s):
Fura-2 pentakis(acetoxymethyl) ester
Documents
$414.12 /1MG
Pack Size Availability Price
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Product Information

Fura 2-AM is a highly versatile fluorescent calcium indicator widely utilized in cellular biology and biochemistry. This compound is particularly effective for measuring intracellular calcium levels, making it an invaluable tool for researchers studying cellular signaling pathways and physiological processes. Its unique structure allows for enhanced sensitivity and specificity, enabling precise detection of calcium fluctuations in live cells. Fura 2-AM is often employed in fluorescence microscopy and flow cytometry, providing researchers with real-time insights into cellular responses to various stimuli, such as neurotransmitters and hormones.

In addition to its application in basic research, Fura 2-AM has significant implications in drug discovery and development, particularly in understanding the mechanisms of action of calcium-modulating drugs. Its ability to provide quantitative data on calcium dynamics can aid in the identification of potential therapeutic targets and the evaluation of drug efficacy. With its robust performance and reliability, Fura 2-AM stands out as a preferred choice for scientists seeking to explore the intricate roles of calcium in cellular functions.

Synonyms
Fura-2 pentakis(acetoxymethyl) ester
CAS Number
108964-32-5
Purity
≥ 95% (HPLC)
Grade
suitable for Hematology & Histology
Molecular Formula
C44H47N3O24
Molecular Weight
1001.85
MDL Number
MFCD00036976
PubChem ID
3364574
Appearance
Yellow or yellow-green powder
Conditions
Store at ≤ -10 °C
General Information
Synonyms
Fura-2 pentakis(acetoxymethyl) ester
CAS Number
108964-32-5
Purity
≥ 95% (HPLC)
Grade
suitable for Hematology & Histology
Molecular Formula
C44H47N3O24
Molecular Weight
1001.85
MDL Number
MFCD00036976
PubChem ID
3364574
Appearance
Yellow or yellow-green powder
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
-
Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Fura 2-AM is widely utilized in research focused on:

  • Calcium Imaging: This compound is primarily used in live-cell imaging to measure intracellular calcium levels. Researchers can visualize calcium dynamics in real-time, which is crucial for understanding cellular signaling pathways.
  • Neuroscience Studies: Fura 2-AM is employed in neuroscience to study neuronal activity and synaptic transmission. Its ability to provide precise calcium measurements helps in unraveling the mechanisms of neurodegenerative diseases.
  • Pharmacological Research: The compound is valuable in drug discovery and development, allowing scientists to assess the impact of new drugs on calcium signaling in various cell types, including cancer cells.
  • Cardiovascular Research: In cardiology, Fura 2-AM is used to investigate calcium handling in cardiac myocytes, aiding in the understanding of heart function and the effects of cardiovascular drugs.
  • Cell Biology Applications: This chemical is also utilized in cell biology to study cell proliferation, differentiation, and apoptosis, providing insights into cellular responses to different stimuli.

Citations