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Catalog Number:
41960
Ethidium homodimer I solution (2 mM in DMSO)
Grade:
suitable for Hematology & Histology
Purity:
≥ 95% (TLC)
Synonym(s):
EtDi, EthD-1, Phenanthridinium, 5,5'-[1,2-ethanediylbis(imino-3,1-propanediyl)]bis(3, 8-diamino-6-phenyl)-,dichloride,dihydrochloride
Hazmat
Documents
$714.47 /1ML
Pack Size Availability Price
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Product Information

Ethidium homodimer I solution (2 mM in DMSO) is a potent fluorescent dye widely utilized in molecular biology and biochemistry for nucleic acid detection and analysis. This compound is particularly effective in staining double-stranded DNA, making it an invaluable tool for researchers in various applications, including gel electrophoresis and live-cell imaging. Its ability to intercalate between DNA bases allows for enhanced fluorescence, providing clear visualization of nucleic acids in complex samples.

Researchers often leverage Ethidium homodimer I in apoptosis studies, where it helps distinguish between viable and non-viable cells by selectively staining dead cells with compromised membranes. Additionally, its compatibility with a range of imaging systems makes it a versatile choice for laboratories focused on genetic research, diagnostics, and drug discovery. With its high sensitivity and specificity, Ethidium homodimer I solution is an essential reagent for any laboratory engaged in DNA-related studies, offering reliable results and facilitating advancements in genetic research.

Synonyms
EtDi, EthD-1, Phenanthridinium, 5,5'-[1,2-ethanediylbis(imino-3,1-propanediyl)]bis(3, 8-diamino-6-phenyl)-,dichloride,dihydrochloride
Purity
≥ 95% (TLC)
Grade
suitable for Hematology & Histology
Molecular Formula
C46H50Cl4N8
Molecular Weight
0
MDL Number
MFCD00210948
Appearance
Red liquid
Conditions
Store at ≤ -10 °C
General Information
Synonyms
EtDi, EthD-1, Phenanthridinium, 5,5'-[1,2-ethanediylbis(imino-3,1-propanediyl)]bis(3, 8-diamino-6-phenyl)-,dichloride,dihydrochloride
Purity
≥ 95% (TLC)
Grade
suitable for Hematology & Histology
Molecular Formula
C46H50Cl4N8
Molecular Weight
0
MDL Number
MFCD00210948
Appearance
Red liquid
Conditions
Store at ≤ -10 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Ethidium homodimer I solution (2 mM in DMSO) is widely utilized in research focused on:

  • Nucleic Acid Staining: Commonly used in gel electrophoresis to visualize DNA and RNA. It intercalates between base pairs, allowing researchers to confirm the presence and integrity of nucleic acids.
  • Cell Viability Assays: Employed in assays to assess cell viability and apoptosis. Ethidium homodimer I can distinguish between live and dead cells, providing crucial data in toxicology and pharmacology studies.
  • Fluorescence Microscopy: Utilized in fluorescence microscopy to study cellular processes. Its bright fluorescence enables detailed observation of cellular structures and functions in live or fixed cells.
  • Genetic Research: A valuable tool in molecular biology for studying gene expression and regulation. It helps in analyzing the effects of various treatments on gene activity.
  • Drug Development: In drug discovery, it aids in screening compounds for their effects on nucleic acids and cellular health, facilitating the identification of potential therapeutic agents.

Citations