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Catalog Number:
37964
CAS Number:
75695-93-1
Isradipine
Purity:
≥ 99% (HPLC)
Synonym(s):
Isopropyl methyl 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate, 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid isopropyl methyl ester
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$110.00 /25MG
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Product Information

Isradipine is a potent calcium channel blocker primarily used in the management of hypertension and angina pectoris. This compound works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. Its unique structure allows for selective targeting of L-type calcium channels, making it effective in lowering systemic vascular resistance and improving blood flow. Isradipine is also recognized for its neuroprotective properties, showing promise in the treatment of conditions such as Alzheimer's disease and other neurodegenerative disorders.

In addition to its cardiovascular applications, Isradipine has been explored in various research settings for its potential to enhance cognitive function and protect against neuronal damage. Its favorable pharmacokinetic profile, including a long half-life and minimal side effects, makes it a preferred choice among healthcare professionals. Researchers and industry professionals can leverage Isradipine's unique properties for innovative therapeutic approaches, particularly in cardiovascular and neurological health.

Synonyms
Isopropyl methyl 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate, 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid isopropyl methyl ester
CAS Number
75695-93-1
Purity
≥ 99% (HPLC)
Molecular Formula
C19H21N3O5
Molecular Weight
371.39
MDL Number
MFCD00153820
PubChem ID
3784
Melting Point
168 - 170 ?C
Appearance
Yellow crystalline powder
Conditions
Store at < -20 °C
General Information
Synonyms
Isopropyl methyl 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate, 4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid isopropyl methyl ester
CAS Number
75695-93-1
Purity
≥ 99% (HPLC)
Molecular Formula
C19H21N3O5
Molecular Weight
371.39
MDL Number
MFCD00153820
PubChem ID
3784
Melting Point
168 - 170 ?C
Appearance
Yellow crystalline powder
Conditions
Store at < -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Isradipine is widely utilized in research focused on:

  • Cardiovascular Health: It is primarily used as an antihypertensive medication, helping to lower blood pressure in patients with hypertension, thereby reducing the risk of heart disease and stroke.
  • Neurological Research: Studies indicate its potential in treating conditions like Alzheimer's disease, as it may improve blood flow to the brain and support cognitive function.
  • Pharmaceutical Development: Isradipine serves as a model compound in drug formulation studies, allowing researchers to explore new delivery methods and dosage forms for better efficacy.
  • Vascular Smooth Muscle Research: It is used in laboratory settings to investigate the mechanisms of vascular smooth muscle contraction and relaxation, aiding in the understanding of various vascular disorders.
  • Clinical Trials: The compound is often included in clinical trials to assess its effectiveness in combination therapies for various cardiovascular and neurological conditions, providing valuable data for future treatments.

Citations