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Catalog Number:
38005
CAS Number:
13010-47-4
Lomustine
Purity:
≥ 98% (HPLC)
Synonym(s):
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
Hazmat
Documents
$64.00 /50MG
Pack Size Availability Price
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Product Information

Lomustine is a potent alkylating agent widely recognized for its application in oncology, particularly in the treatment of various types of cancer, including brain tumors and Hodgkin's lymphoma. This compound operates by interfering with the DNA replication process, effectively halting the growth of cancer cells. Its unique structure, characterized by the presence of a nitrosourea group, enhances its ability to cross the blood-brain barrier, making it particularly valuable in treating central nervous system malignancies. Researchers and healthcare professionals appreciate Lomustine for its efficacy and the potential to be used in combination therapies, which can improve patient outcomes.

In addition to its primary use in cancer treatment, Lomustine has shown promise in veterinary medicine for treating tumors in animals. Its versatility and effectiveness make it a critical component in both human and veterinary oncology. As a well-established chemotherapeutic agent, Lomustine continues to be a focal point of research, with ongoing studies exploring its potential in novel therapeutic regimens. With its proven track record and significant clinical applications, Lomustine remains an essential compound for professionals in the medical and research fields.

Synonyms
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
CAS Number
13010-47-4
Purity
≥ 98% (HPLC)
Molecular Formula
C9H16ClN3O2
Molecular Weight
233.7
MDL Number
MFCD00012392
PubChem ID
3950
Melting Point
89 - 93 ?C
Appearance
Light orange to yellow to green powder to crystal
Conditions
Store at < 0 °C
General Information
Synonyms
1-(2-Chloroethyl)-3-cyclohexyl-1-nitrosourea
CAS Number
13010-47-4
Purity
≥ 98% (HPLC)
Molecular Formula
C9H16ClN3O2
Molecular Weight
233.7
MDL Number
MFCD00012392
PubChem ID
3950
Melting Point
89 - 93 ?C
Appearance
Light orange to yellow to green powder to crystal
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
Yes
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Lomustine is widely utilized in research focused on

  • Cancer Treatment: Primarily used as a chemotherapy agent for treating various types of cancers, including brain tumors and Hodgkin's lymphoma, offering targeted action against malignant cells.
  • Veterinary Medicine: Employed in veterinary oncology for treating tumors in pets, providing an effective option for animal healthcare professionals.
  • Research Applications: Utilized in laboratory settings to study the mechanisms of cancer cell resistance and the development of new therapeutic strategies, aiding researchers in understanding tumor biology.
  • Combination Therapy: Often used in conjunction with other chemotherapeutic agents to enhance treatment efficacy, allowing for a more comprehensive approach to cancer management.
  • Drug Development: Serves as a model compound in the development of new nitrosourea derivatives, facilitating advancements in cancer pharmacology and improving treatment outcomes.

Citations