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Catalog Number:
37869
CAS Number:
152044-54-7
Epothilone B
Purity:
≥ 95% (HPLC)
Documents
$153.63 /5MG
Pack Size Availability Price
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Product Information

Epothilone B is a potent microtubule-stabilizing agent that has garnered significant attention in the field of cancer research and treatment. This compound, a member of the epothilone family, exhibits remarkable efficacy against various cancer cell lines, making it a valuable candidate for developing novel chemotherapeutic agents. Its unique mechanism of action, similar to that of taxanes, allows it to overcome resistance mechanisms often seen in cancer therapies, providing a promising alternative for patients with resistant tumors.

Researchers have utilized Epothilone B in preclinical studies to explore its potential in treating solid tumors, particularly in breast and ovarian cancers. Its ability to induce apoptosis in cancer cells while sparing normal cells highlights its therapeutic advantages. Furthermore, Epothilone B's favorable pharmacokinetic properties, including enhanced solubility and stability, position it as a leading candidate for further clinical development. With ongoing studies, Epothilone B holds the potential to revolutionize cancer treatment protocols and improve patient outcomes.

CAS Number
152044-54-7
Purity
≥ 95% (HPLC)
Molecular Formula
C27H41NO6S
Molecular Weight
507.69
MDL Number
MFCD02101921
PubChem ID
4456137
Melting Point
94 ?C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -40 to -44 ° (C=0.2 in MeOH)
Conditions
Store at < -20 °C
General Information
CAS Number
152044-54-7
Purity
≥ 95% (HPLC)
Molecular Formula
C27H41NO6S
Molecular Weight
507.69
MDL Number
MFCD02101921
PubChem ID
4456137
Melting Point
94 ?C
Appearance
White to almost white powder to crystal
Optical Rotation
[a]20D = -40 to -44 ° (C=0.2 in MeOH)
Conditions
Store at < -20 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Epothilone B is widely utilized in research focused on:

  • Cancer Treatment: This compound is being explored as a potential treatment for various cancers, particularly those resistant to traditional therapies like taxanes. Its unique mechanism of action stabilizes microtubules, disrupting cancer cell division.
  • Drug Development: Researchers are investigating Epothilone B in the development of new chemotherapeutic agents. Its efficacy against certain tumor types makes it a candidate for combination therapies, enhancing treatment outcomes.
  • Biological Research: In cellular biology, it serves as a valuable tool for studying microtubule dynamics and cellular processes, providing insights into cell structure and function.
  • Pharmaceutical Formulations: The compound is being formulated into various drug delivery systems, improving bioavailability and targeting specific cancer cells more effectively.
  • Comparative Studies: Epothilone B is often compared with other microtubule-targeting agents in clinical trials, helping to establish its advantages in terms of efficacy and safety profiles.

Citations