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Catalog Number:
37741
CAS Number:
168555-66-6
Combretastatin A4 phosphate disodium salt
Purity:
≥ 98% (HPLC)
Synonym(s):
Fosbretabulin disodium salt
Documents
$357.34 /20MG
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Product Information

Combretastatin A4 phosphate disodium salt is a potent compound recognized for its significant role in cancer research and therapeutic applications. This compound is a derivative of combretastatin A4, known for its ability to inhibit tumor growth by disrupting the blood supply to tumors, a process known as anti-angiogenesis. Its unique structure allows it to selectively target cancer cells while sparing normal cells, making it a promising candidate for targeted cancer therapies. Researchers have utilized this compound in various studies, demonstrating its effectiveness in reducing tumor size in preclinical models, particularly in breast and prostate cancers.

In addition to its anti-cancer properties, Combretastatin A4 phosphate disodium salt is also being explored for its potential in combination therapies, enhancing the efficacy of existing treatments. Its solubility in aqueous solutions makes it suitable for intravenous administration, providing flexibility in clinical applications. This compound's ability to penetrate tissues and its favorable pharmacokinetic profile further enhance its appeal in the pharmaceutical industry, paving the way for innovative cancer treatment strategies.

Synonyms
Fosbretabulin disodium salt
CAS Number
168555-66-6
Purity
≥ 98% (HPLC)
Molecular Formula
C18H19Na2O8P
Molecular Weight
440.3
MDL Number
MFCD00943911
PubChem ID
76374690
Appearance
White to almost white powder to crystal
Conditions
Store at < 0 °C
General Information
Synonyms
Fosbretabulin disodium salt
CAS Number
168555-66-6
Purity
≥ 98% (HPLC)
Molecular Formula
C18H19Na2O8P
Molecular Weight
440.3
MDL Number
MFCD00943911
PubChem ID
76374690
Appearance
White to almost white powder to crystal
Conditions
Store at < 0 °C
Properties
Additional property information coming soon!
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Safety and Regulations
Hazmat
No
Antibiotic
No
DEA-regulated
No
Warnings
-
Applications

Combretastatin A4 phosphate disodium salt is widely utilized in research focused on:

  • Cancer Treatment: This compound is being studied for its ability to inhibit tumor growth by disrupting the blood supply to tumors, making it a promising candidate for cancer therapies.
  • Drug Development: Researchers are exploring its potential as a lead compound in the development of new anti-cancer drugs, particularly due to its unique mechanism of action compared to traditional chemotherapy agents.
  • Targeted Therapy: Its specificity for tumor vasculature allows for targeted treatment options, reducing side effects commonly associated with non-targeted therapies.
  • Combination Therapy: It is being evaluated in combination with other chemotherapeutic agents to enhance efficacy and overcome drug resistance in various cancer types.
  • Preclinical Studies: The compound is frequently used in preclinical models to assess its pharmacokinetics and pharmacodynamics, providing valuable insights for future clinical trials.

Citations